Spatiotemporal 3D image registration for mesoscale studies of brain development.
Spatiotemporal 3D image registration for mesoscale studies of brain development.
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时空3D图像登记，用于脑发育中尺度研究。
DOI：
10.1038/s41598-022-06871-8
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发表时间：
2022-03-07
影响因子：
4.6
通讯作者：
Koulakov AA
中科院分区：
文献类型：
--
作者：
Shuvaev S;Lazutkin A;Kiryanov R;Anokhin K;Enikolopov G;Koulakov AA
Comparison of brain samples representing different developmental stages often necessitates registering the samples to common coordinates. Although the available software tools are successful in registering 3D images of adult brains, registration of perinatal brains remains challenging due to rapid growth-dependent morphological changes and variations in developmental pace between animals. To address these challenges, we introduce CORGI (Customizable Object Registration for Groups of Images), an algorithm for the registration of perinatal brains. First, we optimized image preprocessing to increase the algorithm’s sensitivity to mismatches in registered images. Second, we developed an attention-gated simulated annealing procedure capable of focusing on the differences between perinatal brains. Third, we applied classical multidimensional scaling (CMDS) to align (“synchronize”) brain samples in time, accounting for individual development paces. We tested CORGI on 28 samples of whole-mounted perinatal mouse brains (P0–P9) and compared its accuracy with other registration algorithms. Our algorithm offers a runtime of several minutes per brain on a laptop and automates such brain registration tasks as mapping brain data to atlases, comparing experimental groups, and monitoring brain development dynamics.
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AMAP是用于注册和分割高分辨率小鼠脑数据的验证管道。
影响因子：
16.6
作者：
Niedworok CJ;Brown AP;Jorge Cardoso M;Osten P;Ourselin S;Modat M;Margrie TW
通讯作者：
Margrie TW
影响因子：
1.9
作者：
Lazutkin, Alexander A.;Shuvaev, Sergey A.;Barykina, Natalia V.
通讯作者：
Barykina, Natalia V.
影响因子：
6.1
作者：
Modat, Marc;Ridgway, Gerard R.;Ourselin, Sebastien
通讯作者：
Ourselin, Sebastien
影响因子：
0.9
作者：
Morozov, A. N.;Lazutkin, A. A.;Anokhin, K. V.
通讯作者：
Anokhin, K. V.
DOI：
10.1109/tpami.1986.4767838
发表时间：
1986-09-01
影响因子：
23.6
作者：
HUERTAS, A;MEDIONI, G
通讯作者：
MEDIONI, G