Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth With Perinatal Human Immunodeficiency Virus in the DC Cohort.

Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth With Perinatal Human Immunodeficiency Virus in the DC Cohort.
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DOI:
10.1093/ofid/ofab308
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发表时间:
2021-07
影响因子:
4.2
通讯作者:
DC Cohort Executive Committee
DC Cohort Executive Committee
中科院分区:
医学3区
文献类型:
--
作者:
Koay WLA;Dirajlal-Fargo S;Levy ME;Kulie P;Monroe A;Castel AD;Rakhmanina NY;DC Cohort Executive Committee

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We conducted a retrospective analysis of 38 children and youth with human immunodeficiency virus (aged 0–19 years) in the United States and report an increased rate of change of BMI-for-age z score after initiating integrase strand transfer inhibitors (+0.19 z score units/year [95% confidence interval, .01–.37]; P = .036) for a median follow-up of 527.5 days. Children and youth with HIV in the United States (n=38) have an increased rate of change of BMI-for-age z-score (+0.19 z-score units/year) after initiating integrase strand transfer inhibitors for a median follow-up of 527.5 days.
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