A bioinformatic assay for pluripotency in human cells.
A bioinformatic assay for pluripotency in human cells.
复制标题
DOI:
10.1038/nmeth.1580
复制
发表时间:
2011-04
期刊:
影响因子:
48
通讯作者:
Loring, Jeanne F.
中科院分区:
文献类型:
--
作者:
Mueller, Franz-Josef;Schuldt, Bernhard M.;Williams, Roy;Mason, Dylan;Altun, Gulsah;Papapetrou, Eirini P.;Danner, Sandra;Goldmann, Johanna E.;Herbst, Arne;Schmidt, Nils O.;Aldenhoff, Josef B.;Laurent, Louise C.;Loring, Jeanne F.
Pluripotent stem cells (PSCs) are defined by their potential to generate all cell types of an organism. The standard assay for pluripotency of mouse PSCs is cell transmission through the germline, but for human PSCs researchers depend on indirect methods such as differentiation into teratomas in immunodeficient mice. Here we report PluriTest, a robust open-access bioinformatic assay of pluripotency in human cells based on their gene expression profiles.
登录
查看更多内容
影响因子:
64.8
作者:
Mueller, Franz-Josef;Laurent, Louise C.;Kostka, Dennis;Ulitsky, Igor;Williams, Roy;Lu, Christina;Park, In-Hyun;Rao, Mahendra S.;Shamir, Ron;Schwartz, Philip H.;Schmidt, Nils O.;Loring, Jeanne F.
通讯作者:
Loring, Jeanne F.
影响因子:
30.8
作者:
Kunarso, Galih;Chia, Na-Yu;Bourque, Guillaume
通讯作者:
Bourque, Guillaume
影响因子:
3.5
作者:
Gandhi, Kaushal S.;McKay, Fiona C.;Booth, David R.
通讯作者:
Booth, David R.
影响因子:
64.5
作者:
Takahashi, Kazutoshi;Yamanaka, Shinya
通讯作者:
Yamanaka, Shinya
DOI:
10.1073/pnas.0308531101
发表时间:
2004-03-23
影响因子:
11.1
作者:
Brunet, JP;Tamayo, P;Mesirov, JP
通讯作者:
Mesirov, JP