Ethnic difference in periodic limb movements in children.
Ethnic difference in periodic limb movements in children.
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儿童周期性肢体运动的种族差异。
DOI：
10.1016/j.sleep.2006.08.009
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发表时间：
2007
期刊：
影响因子：
4.8
通讯作者：
Gozal,David
中科院分区：
文献类型：
--
作者：
O'Brien,LouiseM;Holbrook,CherylR;FayeJones,V;Gozal,David
背景流行病学研究表明，种族是睡眠呼吸紊乱(SDB)的危险因素，非裔美国儿童患SDB的可能性是白人儿童的三倍。睡眠结构和其他常规评估的睡眠参数的种族差异没有得到严格的评估，因此这项研究的目的是比较非裔美国人和高加索儿童的睡眠特征。方法总共向肯塔基州杰斐逊县5-7岁儿童的父母邮寄了41363份睡眠问卷。对有鼾症和无鼾症儿童的家长进行夜间多导睡眠监测。结果9872个家庭收回了完整的问卷，应答率为23%。在这些人中，689人同意接受多导睡眠图检查，542人获得了完整的多导睡眠图(5.7%的调查问卷受访者)。有391名高加索儿童和151名非裔美国儿童接受了夜间多导睡眠图评估，平均年龄为6.7±0.5岁。在睡眠潜伏期、总睡眠时间、睡眠效率或快速眼动(REM)潜伏期方面，两组之间没有差异。非洲裔美国儿童的第三阶段睡眠略有增加(6.0±2.8%比5.4±2.8%；p=0.01)，尽管慢波睡眠的总比例相似。非裔美国儿童的呼吸唤醒指数和总唤醒指数较高(分别为3.6vs.1.4±2.7hvs.1.4vs.1.4±2.7h；p<；0.001和11.5±5.2vs.9.8±4.8/h；p<；0.001)，他们更有可能患有轻度SDB(AHI>；1：34%vs.24%；p=0.017)和SDB(AHI>；5：22.5%vs.7%；p<；0.001)。然而，高加索儿童更有可能在睡眠期间有周期性的腿部运动(PLMS；16.5%对AA的7%；p=0.004)。高加索儿童罹患多发性硬化症的优势比为2.6(95%可信区间为1.3-5.3；p=0.006)。此外，在没有SDB的情况下，高加索儿童患上PLMS的优势比为9.5(95%CI：2.2-39.9；p=0.002)。非洲裔美国儿童更有可能在睡眠期间表现出呼吸障碍，而PLMS在高加索儿童中明显更常见。
BACKGROUNDEpidemiological studies have suggested that ethnicity is a risk factor for sleep-disordered breathing (SDB) and that African-American children are three times more likely than Caucasian children to have SDB. Ethnic differences in sleep architecture and other routinely assessed sleep parameters have not been critically assessed, thus the aim of this study was to compare sleep characteristics in African-American and Caucasian children.METHODSA total of 41,363 sleep questionnaires were mailed to parents of children aged 5–7 years in Jefferson County, KY. Parents of snoring and non-snoring children were invited to have their child undergo overnight polysomnography.RESULTSComplete questionnaires were returned by 9872 families (23% response rate). Of these, 689 agreed to undergo polysomnography, and 542 complete polysomnograms were obtained (5.7% of questionnaire respondents). There were 391 Caucasian and 151 African-American children with a mean age of 6.7±0.5 years who underwent overnight polysomnographic evaluation. No differences between groups were observed for sleep latency, total sleep time, sleep efficiency, or rapid eye movement (REM) latency. African-American children had slightly increased stage 3 sleep (6.0±2.8% vs. 5.4±2.8%; p=0.01), although the total proportion of slow wave sleep was similar. Higher respiratory arousal index (3.6±6.5/h vs. 1.4±2.7/h; p<0.001) and total arousal index (11.5±5.2/h vs. 9.8±4.8/h; p<0.001) emerged in African-American children, who were more likely to have mild SDB (AHI>1:34% in African-American vs. 24% in Caucasian; p=0.017) and SDB (AHI>5: 22.5% vs. 7%; p<0.001). However, Caucasian children were more likely to have periodic leg movements during sleep (PLMS; 16.5% vs. 7% in AA; p=0.004). The odds ratio for a Caucasian child to have PLMS was 2.6 (95% confidence interval (CI) 1.3–5.3; p=0.006). Furthermore, in the absence of SDB, the odds ratio for a Caucasian child to have PLMS was 9.5 (95% CI: 2.2–39.9; p=0.002).CONCLUSIONSAfrican-American and Caucasian children have similar sleep architecture. African-American children are more likely to display respiratory disturbances during sleep, while PLMS are significantly more prevalent among Caucasian children.
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DOI：
10.1164/ajrccm.155.1.9001310
发表时间：
1997-01-01
影响因子：
24.7
作者：
Redline, S;Tishler, PV;Spry, K
通讯作者：
Spry, K
影响因子：
5.6
作者：
Tauman, R;O'Brien, LM;Gozal, D
通讯作者：
Gozal, D
影响因子：
4.2
作者：
BONNET, MH
通讯作者：
BONNET, MH
影响因子：
5.6
作者：
Montgomery-Downs, HE;O'Brien, LM;Gozal, D
通讯作者：
Gozal, D
DOI：
10.1164/ajrccm/146.5_pt_1.1235
发表时间：
1992-11-01
期刊：
AMERICAN REVIEW OF RESPIRATORY DISEASE
影响因子：
--
作者：
MARCUS, CL;OMLIN, KJ;WARD, SLD
通讯作者：
WARD, SLD