Spatial distribution and determinants of health loss from Kashin-Beck disease in Bin County, Shaanxi Province, China.
Spatial distribution and determinants of health loss from Kashin-Beck disease in Bin County, Shaanxi Province, China.
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陕西省宾县大骨节病空间分布及健康损失影响因素
DOI：
10.1186/s12889-021-10407-6
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发表时间：
2021-02-19
影响因子：
4.5
通讯作者：
Kong C
中科院分区：
文献类型：
--
作者：
Wang J;Wang X;Li H;Yang L;Li Y;Kong C
大骨节病是中国的主要地方病之一，严重影响人们的身体健康和生活质量。了解大骨节病健康损失的空间分布及其影响因素，有助于识别大骨节病高危地区和高危人群，制定针对性干预措施。方法收集陕西省宾县大骨节病患者资料，对大骨节病健康损失的空间格局进行估计和分析。残疾生活年数(YLDs)指数被用来衡量大骨节病造成的健康损失。空间自相关方法，包括Global Moran‘s I和Local Moran’s I，被用来描述和绘制健康损失的空间集群。并收集基本个人信息和环境样本，探讨大骨节病健康损失的自然和社会影响因素。结果大骨节病健康损失的YLDs估计显示，大骨节病II级患者和50岁以上 患者是宾县大骨节病健康损失的主要贡献者。不同性别间无显著差异。大骨节病年死亡率和年死亡率的空间格局在全球和地方尺度上都表现出明显的聚集性。西南部和东部地区的村庄健康损失较高，而北部地区的村庄健康损失较低。这种聚集性与土壤有机结合态硒和大骨节病患者的贫困率显著相关。结论今后大骨节病的防治应以土壤有机结合态硒含量高、经济条件差的病区为重点。这一发现也为进一步探讨大骨节病的病因提供了重要信息。
BackgroundKashin-Beck disease (KBD) is one of the major endemic diseases in China, which severely impacts the physical health and life quality of people. A better understanding of the spatial distribution of the health loss from KBD and its influencing factors will help to identify areas and populations at high risk so as to plan for targeted interventions.MethodsThe data of patients with KBD at village-level were collected to estimate and analyze the spatial pattern of health loss from KBD in Bin County, Shaanxi Province. The years lived with disability (YLDs) index was applied as a measure of health loss from KBD. Spatial autocorrelation methodologies, including Global Moran’s I and Local Moran’s I, were used to describe and map spatial clusters of the health loss. In addition, basic individual information and environmental samples were collected to explore natural and social determinants of the health loss from KBD.ResultsThe estimation of YLDs showed that patients with KBD of grade II and patients over 50 years old contributed most to the health loss of KBD in Bin County. No significant difference was observed between two genders. The spatial patterns of YLDs and YLD rate of KBD were clustered significantly at both global and local scales. Villages in the southwestern and eastern regions revealed higher health loss, while those in the northern regions exhibited lower health loss. This clustering was found to be significantly related to organically bound Se in soil and poverty rate of KBD patients.ConclusionsOur results suggest that future treatment and prevention of KBD should focus on endemic areas with high organically bound Se in soil and poor economic conditions. The findings can also provide important information for further exploration of the etiology of KBD.
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DOI：
10.2471/blt.06.033035
发表时间：
2007-06-01
期刊：
Bulletin of the World Health Organization: International Journal of Public Health
影响因子：
--
作者：
Jia, Tie-Wu;Zhou, Xiao-Nong;Wu, Xiao-Hua
通讯作者：
Wu, Xiao-Hua
影响因子：
3.3
作者：
Jiang, Yongwen;Hesser, Jana Earl
通讯作者：
Hesser, Jana Earl
影响因子：
3.6
作者：
ANSELIN, L
通讯作者：
ANSELIN, L
达卡贫民窟的自我评估心理健康的空间流行病学分析。
影响因子：
4.9
作者：
Gruebner O;Khan MM;Lautenbach S;Müller D;Kraemer A;Lakes T;Hostert P
通讯作者：
Hostert P
南非农村中风的疾病负担：估计发病率，死亡率和残疾调整的终身年份。
影响因子：
2.6
作者：
Maredza M;Bertram MY;Tollman SM
通讯作者：
Tollman SM