Paternal support and preterm birth, and the moderation of effects of chronic stress: a study in Los Angeles county mothers.

Paternal support and preterm birth, and the moderation of effects of chronic stress: a study in Los Angeles county mothers.
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DOI:
10.1007/s00737-009-0135-9
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发表时间:
2010-08
影响因子:
4.5
通讯作者:
Ritz, Beate R.
Ritz, Beate R.
中科院分区:
医学2区
文献类型:
--
作者:
Ghosh, Jo Kay C.;Wilhelm, Michelle H.;Dunkel-Schetter, Christine;Lombardi, Christina A.;Ritz, Beate R.

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母亲心理社会压力是早产的一个重要风险因素,但支持性干预在很大程度上是不成功的。本研究的目的是评估孕期支持如何影响早产风险,并可能改善孕妇的慢性应激、生活事件应激或怀孕焦虑的影响。我们对1,027名单身早产儿和1,282名足月正常体重对照进行了研究,这些研究来自于一项基于人群的回溯性病例对照研究,研究对象是2003年在加利福尼亚州洛杉矶县分娩的妇女,这些妇女大多是拉丁裔人口(包括在美国出生的和移民的)。我们使用Logistic回归来评估怀孕期间来自婴儿父亲的支持是否会影响分娩结果以及慢性压力、怀孕焦虑和生活事件压力的影响。调整后的早产风险随着更好的支持而降低(OR 0.73[95%CI 0.52,1.01])。慢性压力(OR 1.46[95%CI 1.11,1.92])、对正常分娩缺乏信心(OR 1.57[95%CI 1.17,2.12])和对婴儿健康的担忧(OR 1.67[95%CI 1.30,2.14])会增加早产风险,但生活事件与早产无关。我们的数据还表明,父亲的支持可能会改变慢性压力对早产风险的影响,在缺乏支持的母亲中,中到高度压力的母亲早产的几率增加(OR 2.15[95%CI 0.92,5.03]),但有较大支持的妇女患中到高度慢性压力的风险没有增加(OR 1.13[95%CI 0.94,1.35])。父亲的支持可能会缓和慢性压力对早产风险的影响。
Maternal psychosocial stress is an important risk factor for preterm birth, but support interventions have largely been unsuccessful. The objective of this study is to assess how support during pregnancy influences preterm birth risk and possibly ameliorates the effects of chronic stress, life event stress, or pregnancy anxiety in pregnant women. We examined 1,027 singleton preterm births and 1,282 full-term normal weight controls from a population-based retrospective case–control study of Los Angeles County, California women giving birth in 2003, a mostly Latina population (both US-born and immigrant). We used logistic regression to assess whether support from the baby’s father during pregnancy influences birth outcomes and effects of chronic stress, pregnancy anxiety, and life event stress. Adjusted odds of preterm birth decreased with better support (OR 0.73 [95%CI 0.52, 1.01]). Chronic stress (OR 1.46 [95%CI 1.11, 1.92]), low confidence of a normal birth (OR 1.57 [95% CI 1.17, 2.12]), and fearing for the baby’s health (OR 1.67 [95%CI 1.30, 2.14]) increased preterm birth risk, but life events showed no association. Our data also suggested that paternal support may modify the effect of chronic stress on the risk of preterm birth, such that among mothers lacking support, those with moderate-to-high stress were at increased odds of delivering preterm (OR 2.15 [95%CI 0.92, 5.03]), but women with greater support had no increased risk with moderate-to-high chronic stress (OR 1.13 [95%CI 0.94, 1.35]). Paternal support may moderate the effects of chronic stress on the risk of preterm delivery.
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