Characteristics of patients with primary open angle glaucoma and normal tension glaucoma at a university hospital: a cross-sectional retrospective study
Characteristics of patients with primary open angle glaucoma and normal tension glaucoma at a university hospital: a cross-sectional retrospective study
复制标题
某大学医院原发性开角型青光眼和正常眼压性青光眼患者的特征：一项横断面回顾性研究
作者：
Yu Yokoyama;K. Maruyama;Hideyuki Konno;Sayaka Hashimoto;Mai Takahashi;Hiroko Kayaba;Taiki Kokubun;T. Nakazawa
青光眼患者的特点和他们对治疗的反应可能因机构、地区和国家而异。因此，临床医生应该了解患者的特殊性。在这里，我们介绍原发性开角型青光眼（POAG）和正常眼压性青光眼（NTG）患者在一个主要的大学hospitalinjapan.MethodsThis研究包括523眼523 POAG和NTG患者进行了全面的临床眼科评价在东北大学医院。回顾性收集年龄、性别、视力、眼压、Humphrey视野分析仪测量的平均偏差（MD）和MD斜率等临床特征。根据MD数据计算MD斜率，其中包括MD的首次基线测量值和随后的4次连续可靠的MD测量值。在无屈光手术史（包括眼内透镜植入）的亚组中分析屈光不正。在低血糖患者组中分别分析患者特征，（<15 mmHg）和高IOP（≥15 mmHg）和MD斜率≥-1.0和<-1.0 dB/year.ResultsMean年龄，视力（中位数），IOP，治疗前IOP（根据患者病史），屈光不正和MD分别为61.7 ± 12.5岁，-0.08（四分位距−0.08至0.05）LogMAR，分别为13.87 ± 3.37 mmHg、18.35 ± 6.26 mmHg、−4.48 ± 3.81屈光度和−11.73 ± 8.83 dB。POAG和NTG患者的平均年龄（63.4 ± 12.4 vs. 60.7 ± 12.5岁，P < 0.01）、视力、IOP（14.95 ± 4.20 vs. 13.21 ± 2.54 mmHg，P < 0.01）和MD（−13.85 ± 9.32 vs. −10.45 ± 8.27 dB，P < 0.01）存在显著差异。有趣的是，低IOP组的MD斜率比高IOP组略陡，尽管差异无统计学意义（-0.85 vs.-0.70 dB/年，P = 0.31）。MD斜率<−1.0 dB/year组的基线MD显著差于MD斜率≥−1.0 dB/year组（−11.56 vs. −7.64 dB/year，P < 0.01）.结论我们确定了大学医院青光眼患者的特征，这些特征可能反映了该机构的专业性质。
BackgroundThe characteristics of glaucoma patients and their response to therapy may differ by institution, region and country. Therefore, clinicians should understand the distinctiveness of their patients. Here, we profile primary open angle glaucoma (POAG) and normal tension glaucoma (NTG) patients at a major university hospital in Japan.MethodsThis study included 523 eyes from 523 POAG and NTG patients who underwent full clinical ophthalmologic evaluations at Tohoku University Hospital. Clinical characteristics such as age, sex, visual acuity, intraocular pressure, Humphrey field analyzer-measured mean deviation (MD) and MD slope were collected retrospectively. MD slope was calculated from MD data that included the first baseline measurement of MD and 4 subsequent, consecutive, reliable measurements of MD. Refractive error was analyzed in a subgroup with no history of refractive surgery, including intraocular lens implantation. Patient characteristics were analyzed separately in the groups of patients with low (<15 mmHg) and high IOP (≥15 mmHg) and in the groups with MD slope ≥−1.0 and <−1.0 dB/year.ResultsMean age, visual acuity (median), IOP, pre-treatment IOP (from patient history), refractive error and MD were 61.7 ± 12.5 years, −0.08 (interquartile range −0.08 to 0.05) LogMAR, 13.87 ± 3.37 mmHg, 18.35 ± 6.26 mmHg, −4.48 ± 3.81 diopters and −11.73 ± 8.83 dB, respectively. POAG and NTG patients had significant differences in mean age (63.4 ± 12.4 vs. 60.7 ± 12.5 years, P < 0.01), visual acuity, IOP (14.95 ± 4.20 vs. 13.21 ± 2.54 mmHg, P < 0.01) and MD (−13.85 ± 9.32 vs. −10.45 ± 8.27 dB, P < 0.01). Interestingly, MD slope was slightly steeper in the low-IOP group than in the high-IOP group, although the difference was not statistically significant (−0.85 vs. −0.70 dB/year, P = 0.31). Baseline MD was significantly worse in the group with MD slope <−1.0 dB/year than in the group with MD slope ≥−1.0 dB/year (−11.56 vs. −7.64 dB/year, P < 0.01).ConclusionsWe identified characteristics of glaucoma patients at a university hospital that may reflect the specialized nature of such an institution.
登录
查看更多内容
影响因子：
--
作者：
LESKE, MC;CONNELL, AMS;GEORGE, TW
通讯作者：
GEORGE, TW
影响因子：
--
作者：
Heijl, A;Leske, MC;Hussein, M
通讯作者：
Hussein, M
影响因子：
4.1
作者：
Quigley, HA
通讯作者：
Quigley, HA
高眼压患者的视乳头旁脉络膜视网膜萎缩。
DOI：
10.1001/archopht.1997.01100160679003
发表时间：
1997
期刊：
Archives of ophthalmology (Chicago, Ill. : 1960)
影响因子：
--
作者：
Tezel,G;Kolker,AE;Wax,MB;Kass,MA;Gordon,M;Siegmund,KD
通讯作者：
Siegmund,KD