Mycoplasma pneumoniae-associated bronchiolitis causing severe restrictive lung disease in adults: report of three cases and literature review.
Mycoplasma pneumoniae-associated bronchiolitis causing severe restrictive lung disease in adults: report of three cases and literature review.
复制标题
肺炎支原体相关的支气管炎引起了成人严重限制性肺部疾病：三例病例和文献综述的报告。
DOI：
10.1378/chest.115.4.1188
复制
发表时间：
1999-04
期刊：
影响因子：
9.6
通讯作者：
Schwarz MI
中科院分区：
文献类型：
--
作者：
Chan ED;Kalayanamit T;Lynch DA;Tuder R;Arndt P;Winn R;Schwarz MI
To characterize adult Mycoplasma pneumoniae-induced bronchiolitis requiring hospitalization. We encountered an adult patient with severe bronchiolitis in the absence of pneumonia due to M pneumoniae. To determine the relative frequency of such a condition, we retrospectively reviewed the medical records of adults over a 4-year period with a hospital discharge diagnosis of “bronchiolitis” from a university hospital. University Hospital of the University of Colorado Health Sciences Center, Denver, CO. From 1994 to 1998, 10 adult inpatients were identified with a diagnosis of bronchiolitis. There were two with respiratory bronchiolitis, one with panbronchiolitis, one patient with bronchiolitis obliterans organizing pneumonia (BOOP), and six with acute inflammatory bronchiolitis. Including the initial patient, three had a definitive clinical diagnosis of Mycoplasma-associated bronchiolitis. The three adult patients with bronchiolitis due to M pneumoniae are unusual because they occurred in the absence of radiographic features of a lobar or patchy alveolar pneumonia. Hospital admission was occasioned by the severity of symptoms and gas exchange abnormalities. One patient had bronchiolitis as well as organizing pneumonia (BOOP) that responded favorably to corticosteroid treatment. The other two had high-resolution CT findings diagnostic of an acute inflammatory bronchiolitis. One of the patients with inflammatory bronchiolitis had an unusual pattern of marked ventilation and perfusion defects localized predominantly to the left lung. All three had restrictive ventilatory impairment on physiologic testing. In adults, Mycoplasma-associated bronchiolitis without pneumonia is rarely reported, but in hospitalized patients, it may be more common than expected and may be associated with severe physiologic disturbances.
登录
查看更多内容
影响因子：
9.6
作者：
CORDIER, JF;LOIRE, R;BRUNE, J
通讯作者：
BRUNE, J
DOI：
10.1055/s-2007-1006266
发表时间：
1992-03-01
期刊：
SEMINARS IN RESPIRATORY MEDICINE
影响因子：
--
作者：
CHURG, A
通讯作者：
CHURG, A
DOI：
10.1099/00221287-139-10-2431
发表时间：
1993-10-01
期刊：
JOURNAL OF GENERAL MICROBIOLOGY
影响因子：
--
作者：
CADIEUX, N;LEBEL, P;BROUSSEAU, R
通讯作者：
BROUSSEAU, R
影响因子：
--
作者：
HAWLEY, PC;WHITCOMB, ME
通讯作者：
WHITCOMB, ME
影响因子：
1.1
作者：
FRALEY, DS;RUBEN, FL;DONNELLY, EJ
通讯作者：
DONNELLY, EJ