The Current State of Deep Brain Stimulation for Chronic Pain and Its Context in Other Forms of Neuromodulation.

The Current State of Deep Brain Stimulation for Chronic Pain and Its Context in Other Forms of Neuromodulation.
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DOI:
10.3390/brainsci8080158
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发表时间:
2018-08-20
期刊:
影响因子:
3.3
通讯作者:
Aziz T
Aziz T
中科院分区:
医学4区
文献类型:
--
作者:
Farrell SM;Green A;Aziz T

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慢性顽固性疼痛对那些被触摸的人来说是虚弱的,影响到5%的人口。自20世纪70年代至80年代以来,深部脑刺激(DBS)作为治疗慢性疼痛的中央植入式神经刺激已不再受欢迎,一些神经外科医生倾向于将运动皮质刺激作为“最后的机会沙龙”。本文综述了DBS作为慢性疼痛治疗方法的现有数据和专业意见,并将其与其他神经调节疗法联系起来。我们建议DBS及其新的靶点,即前扣带皮质(ACC),不应因为缺乏高质量的研究数据而被列入黑名单,因为高质量的研究数据往往无法捕捉到治疗的优点。
Chronic intractable pain is debilitating for those touched, affecting 5% of the population. Deep brain stimulation (DBS) has fallen out of favour as the centrally implantable neurostimulation of choice for chronic pain since the 1970–1980s, with some neurosurgeons favouring motor cortex stimulation as the ‘last chance saloon’. This article reviews the available data and professional opinion of the current state of DBS as a treatment for chronic pain, placing it in the context of other neuromodulation therapies. We suggest DBS, with its newer target, namely anterior cingulate cortex (ACC), should not be blacklisted on the basis of a lack of good quality study data, which often fails to capture the merits of the treatment.
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