Fatigue and health related quality of life in children and adolescents with cancer.
Fatigue and health related quality of life in children and adolescents with cancer.
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儿童和癌症青少年的疲劳和与健康相关的生活质量。
DOI：
10.1016/j.ejon.2017.05.001
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发表时间：
2017-08
期刊：
影响因子：
--
通讯作者：
Nascimento LC
中科院分区：
文献类型：
--
作者：
Nunes MDR;Jacob E;Bomfim EO;Lopes-Junior LC;de Lima RAG;Floria-Santos M;Nascimento LC
该研究检查了疲劳的不同维度（一般，睡眠/休息，认知），健康相关的生活质量（身体，情感，认知，社会），以及巴西住院儿童和青少年癌症患者疲劳和HRQL之间的关系。参与者是从巴西东南部一家综合性癌症护理医院的儿科肿瘤住院部招募的。他们在住院期间完成了一次PedsQL多维疲劳量表和PedsQL生活质量量表（通用和癌症模块）。大多数（66.7%）参与者（n=38;平均年龄12.1 ± 2.9岁）在0 - 100量表上的总疲劳评分< 75;平均总疲劳评分为63.8 ± 18.5。大多数（72.2%通用; 83.3%癌症模块）在0至100量表上的PedsQL总分< 75。通用模块的平均PedsQL评分（61.1 ± 17.0）与癌症模块的平均PedsQL评分（59.1 ± 16.7）相似。总疲劳与生活质量（r=0.63，p = 0.000）和癌症模块（r=0.74，p = 0.000）之间存在显著相关性。该研究首次报告了巴西住院儿童和青少年癌症患者的疲劳和健康相关生活质量。与世界上其他儿童的经历相似，我们的研究结果表明，患有癌症的儿童和青少年存在与低HRQL相关的疲劳问题。未来的研究建议检查干预措施（运动，休闲活动），可能会减轻疲劳和改善儿童癌症患者的HRQL。
The study examined the different dimensions of fatigue (general, sleep/rest, cognitive), health related quality of life (physical, emotional, cognitive, social), and the relationships between fatigue and HRQL in hospitalized children and adolescents with cancer in Brazil. Participants were recruited from a pediatric oncology inpatient unit in a comprehensive cancer care hospital in southeast Brazil. They completed the PedsQL Multidimensional Fatigue Scale and the PedsQL Inventory of Quality of Life (Generic and Cancer module) once during hospitalization. The majority (66.7%) of the participants (n=38; mean age 12.1 ± 2.9 years) had total fatigue scores < 75 on 0 to 100 scale; with the mean total fatigue score of 63.8 ± 18.5. The majority (72.2% generic; 83.3% cancer modules) had total PedsQL scores < 75 on 0 to 100 scale. The mean PedsQL score on generic module (61.1 ± 17.0) was similar to the mean PedsQL score cancer module (59.1 ± 16.7). Significant correlations were found between total fatigue and quality of life generic (r=0.63, p = 0.000) and cancer module (r=0.74, p = 0.000). The study is the first to report fatigue and health related quality of life in hospitalized children and adolescents with cancer in Brazil. Similar to experiences of other children in the world, our findings indicate that children and adolescents with cancer had problems with fatigue that were associated with low HRQL. Future studies are recommended to examine interventions (exercise, leisurely activities) that may alleviate fatigue and improve HRQL in pediatric patients with cancer.
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影响因子：
2.6
作者：
Gibson, F;Garnett, M;Sepion, B
通讯作者：
Sepion, B
DOI：
10.1177/1043454203253969
发表时间：
2003-07-01
期刊：
Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses
影响因子：
--
作者：
Hicks, Julie;Bartholomew, Joy;Hutto, C J
通讯作者：
Hutto, C J
影响因子：
2.1
作者：
De Bolle, Marleen;De Clercq, Barbara;Benoit, Yves
通讯作者：
Benoit, Yves
影响因子：
1.9
作者：
Gedaly-Duff, Vivian;Lee, Kathryn A.;Johnson, Kyle P.
通讯作者：
Johnson, Kyle P.
影响因子：
2.6
作者：
Genc, Rabia Ekti;Conk, Zeynep
通讯作者：
Conk, Zeynep