Clinical presentations and management of COVID-19 infected children seen in a district health facility in Kambia, northern Sierra Leone.
Clinical presentations and management of COVID-19 infected children seen in a district health facility in Kambia, northern Sierra Leone.
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DOI：
10.11604/pamj.supp.2020.37.28.26312
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Watson-Jones D
中科院分区：
文献类型：
--
作者：
Adetola HH;Ishola D;Afolabi MO;Bangura J;Sesay IG;Pearce R;Garrick I;Kamara B;Leigh B;Greenwood B;Watson-Jones D
报告撒哈拉以南非洲儿童COVID-19临床表现的研究很少，特别是来自资源有限的国家。该病例系列报告了在塞拉利昂一家地区医院就诊的COVID-19确诊儿童病例的人口统计学和临床特征以及实验室检查结果。这是塞拉利昂北方坎比亚区一家二级医院管理的9例COVID-19儿科病例的报告。在COVID-19应对小组确定一名受感染的成年人后，通过接触者追踪发现了每名儿童。在介绍，临床课程，治疗和病人的结果的临床症状进行了讨论的背景下，在一个典型的西非地区医院的设施。于2020年4月24日至9月20日期间到医院就诊并入住医院隔离中心的30名确诊COVID-19感染者中，有9名为儿科年龄组。儿童的平均年龄（SD）和中位数（IQR）分别为69.0 ± 51.7个月和84.0（10.5，108.0）个月; 5例（55.6%）为男性。这些儿童无症状或仅有轻微疾病，没有人需要鼻内吸氧或呼吸支持。在5名有症状的儿童中，最常见的症状是发热（40%）和咳嗽（40%）。所有患儿的血红蛋白、血小板和白色血细胞（WBC）计数均正常。4名儿童的疟疾检测呈阳性，并接受了完整疗程的抗疟疾药物治疗。没有儿童接受类固醇或特异性抗COVID-19治疗。所有儿童都在隔离中心呆了14天，并在初步诊断后两周重新进行了COVID-19检测。自出院以来，没有报告任何并发症。在塞拉利昂的一个农村社区发现的COVID-19感染病例中，儿童的比例为30%。发烧是最常见的症状，40%的受感染儿童被证实患有疟疾。这对疟疾流行环境中COVID-19的诊断以及如何最好地管理COVID-19大流行期间出现发热的儿童具有重要意义。
Studies reporting the clinical presentations of COVID-19 in children in sub-Saharan Africa are few, especially from resource-constrained countries. This case series reports the demographic and clinical characteristics and laboratory findings of confirmed cases of COVID-19 in children seen at a district hospital in Sierra Leone. This is a report of nine COVID-19 paediatric cases managed at a secondary level hospital in Kambia District, Northern Sierra Leone. Each child was detected by contact tracing after an infected adult was identified by the COVID-19 response team. The clinical symptoms at presentation, clinical courses, and treatments instituted and patient outcomes are discussed in the context of the facilities available at a typical West African district hospital. Nine out of 30 individuals with confirmed COVID-19 infection who presented to the hospital from 24 April to 20 September 2020 and who were admitted to the isolation center of the hospital were in the paediatric age group. The mean age (SD) and median (IQR) of the children were 69.0 ± 51.7months and 84.0 (10.5, 108.0) months, respectively; five (55.6%) were males. The children were asymptomatic or only had mild illnesses and none required intranasal oxygen or ventilatory support. In the five symptomatic children, the most common symptoms were fever (40%) and cough (40%). All children had normal haemoglobin, platelet and white blood cell (WBC) count. Four children had a positive malaria test and were treated with a complete course of anti-malaria medications. No child received steroid or had specific anti-COVID-19 treatment. All children stayed in the isolation center for 14 days and were re-tested for COVID-19 two weeks after initial diagnosis. No complications have been reported in any of them since discharge. The proportion of children among COVID-19 infected cases seen in a rural community in Sierra Leone was 30%. Fever was the most common symptom and malaria was confirmed in 40% of the infected children. This has significant implication on the diagnosis of COVID-19 in malaria-endemic settings and on how best to manage children who present with fever during the COVID-19 pandemic.
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影响因子：
64.8
作者：
Li W;Moore MJ;Vasilieva N;Sui J;Wong SK;Berne MA;Somasundaran M;Sullivan JL;Luzuriaga K;Greenough TC;Choe H;Farzan M
通讯作者：
Farzan M
DOI：
10.3760/cma.j.issn.0578-1310.2020.0001
发表时间：
2020-02-02
期刊：
Zhonghua er ke za zhi = Chinese journal of pediatrics
影响因子：
--
作者：
Fang, F;Luo, X P
通讯作者：
Luo, X P
中国武汉市 138 例 2019 新型冠状病毒感染肺炎住院患者的临床特征。
影响因子：
120.7
作者：
Wang, Dawei;Hu, Bo;Peng, Zhiyong
通讯作者：
Peng, Zhiyong
影响因子：
64.8
作者：
Wu, Fan;Zhao, Su;Zhang, Yong-Zhen
通讯作者：
Zhang, Yong-Zhen
影响因子：
17.1
作者：
Pierce CA;Preston-Hurlburt P;Dai Y;Aschner CB;Cheshenko N;Galen B;Garforth SJ;Herrera NG;Jangra RK;Morano NC;Orner E;Sy S;Chandran K;Dziura J;Almo SC;Ring A;Keller MJ;Herold KC;Herold BC
通讯作者：
Herold BC