Silent versus symptomatic ischemia during a thallium-201 exercise test.

Silent versus symptomatic ischemia during a thallium-201 exercise test.
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铊 201 运动试验期间无症状缺血与有症状缺血的比较。

DOI:
10.1016/0002-9149(91)90316-d
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发表时间:
1991
期刊:
The American journal of cardiology
影响因子:
--
通讯作者:
P. Laraia
P. Laraia
中科院分区:
--
文献类型:
--
作者:
M. Travin;A. R. Flores;C. Boucher;J. Newell;P. Laraia

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将 134 名在铊 201 运动测试中出现再分布但未经历心绞痛的患者(第 1 组)与 134 名在测试期间出现心绞痛但也出现再分布的患者(第 2 组)进行比较。这些组的年龄、性别和峰值运动心率相匹配。尽管两组患者都达到了相当的运动水平,但第 1 组患者缺血性 ST 段压低的发生频率较低(53% vs 71%,p < 0.005)且严重程度较低(0.15 ± 0.13 vs 0.20 ± 0.13 mV,p < 0.005)。在再分布缺陷的数量、最严重的再分布缺陷的严重性以及范围和严重性的缺血指数综合方面,第 1 组的缺血铊 201 图像也较少。第 1 组患者接受早期血运重建的可能性较小(12% vs 29%,p < 0.005),但在其余患者中,不良心脏事件的发生率相似(21% vs 29%,p = 不显着)。通过多变量分析,第 1 组中只有缺血指数与早期血运重建相关(p = 0.0017),而最大预测心率百分比在第 2 组中相关性最佳(p = 0.0003)。在第 1 组中,肺/心脏铊 201 摄取比率与非致命性心肌梗塞或心源性死亡的结果相关性最好(p = 0.0024);在第 2 组中,存在固定的左心室扩张(p = 0.0022)。因此,运动引起的铊 201 重新分布而无心绞痛的患者比发生心绞痛的患者具有更少的缺血。他们也不太可能接受早期血运重建,但他们的预后在其他方面与测试期间出现心绞痛的患者相似。
One hundred thirty-four patients with redistribution on a thallium-201 exercise test who did not experience angina (group 1) were compared with 134 patients also having redistribution who had angina during the test (group 2). The groups were matched by age, sex, and peak exercise heart rate. Although patients in both groups achieved an equivalent exercise level, patients in group 1 had less frequent (53 vs 71%, p < 0.005) and less severe (0.15 ± 0.13 vs 0.20 ± 0.13 mV, p < 0.005) ischemic ST-segment depression. Group 1 also had less ischemic thallium-201 images in terms of the number of redistributing defects, the severity of the worst redistributing defect, and an ischemic index composite of both extent and severity. Patients in group 1 were less likely to undergo early revascularization (12 vs 29%, p < 0.005), but in the remaining patients the occurrence of adverse cardiac events was similar (21% vs 29%, p = not significant). By multivariate analysis, only the ischemic index correlated with early revascularization in group 1 (p = 0.0017), whereas the percent maximal predicted heart rate correlated best in group 2 (p = 0.0003). In group 1 the ratio of lung/heart thallium-201 uptake correlated best with an outcome of nonfatal myocardial infarction or cardiac death (p = 0.0024); in group 2 the presence of fixed left ventricular dilatation did (p = 0.0022). Thus, patients with exercise-induced thallium-201 redistribution without angina have less ischemia than patients experiencing angina. They are also less likely to undergo early revascularization, but their prognosis is otherwise similar to patients with angina during the test.
心肌灌注不足的程度和严重程度作为疑似冠状动脉疾病患者预后的预测因子。
DOI: 10.1016/s0735-1097(86)80454-5
发表时间: 1986
影响因子: 24
作者:
Ladenheim,ML;Pollock,BH;Rozanski,A;Berman,DS;Staniloff,HM;Forrester,JS;Diamond,GA
通讯作者: Diamond,GA
努力程度对有症状冠状动脉疾病运动铊 201 压力测试敏感性的影响。
DOI: 10.1016/0002-9149(89)90278-6
发表时间: 1989
期刊: The American journal of cardiology
影响因子: --
作者:
Esquivel,L;Pollock,SG;Beller,GA;Gibson,RS;Watson,DD;Kaul,S
通讯作者: Kaul,S
跑步机上的无痛运动 ST 偏差:长期预后。
DOI: 10.1016/0735-1097(89)90459-2
发表时间: 1989
影响因子: 24
作者:
Mark,DB;Hlatky,MA;Califf,RM;MorrisJr,JJ;Sisson,SD;McCants,CB;Lee,KL;HarrellJr,FE;Pryor,DB
通讯作者: Pryor,DB