Patent ductus arteriosus: are current neonatal treatment options better or worse than no treatment at all?
Patent ductus arteriosus: are current neonatal treatment options better or worse than no treatment at all?
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DOI：
10.1053/j.semperi.2011.09.022
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发表时间：
2012-04
影响因子：
3.4
通讯作者：
Murphy GM
中科院分区：
文献类型：
--
作者：
Clyman RI;Couto J;Murphy GM
Although a moderate-size PDA needs to be closed by the time a child is 1–2 years old, there is great uncertainty about whether it needs to be closed during the neonatal period. While 95% of neonatologists believe that a moderate-size PDA should be closed if it persists in infants (born before 28 weeks) who still require mechanical ventilation, the number that treat a PDA when it occurs in infants that do not require mechanical ventilation varies widely. Both the high likelihood of spontaneous ductus closure and the absence of RCTs, specifically addressing the risks and benefits of neonatal ductus closure, adds to the current uncertainty. New information suggests that early pharmacologic treatment has several important short-term benefits for the preterm newborn. On the other hand, ductus ligation, while eliminating the detrimental effects of a PDA on lung development, may create its own set of morbidities that counteract many of the benefits derived from ductus closure.
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影响因子：
2.9
作者：
Benitz, W. E.
通讯作者：
Benitz, W. E.
影响因子：
3.6
作者：
Chang, Ling Yi;McCurnin, Donald;Clyman, Ronald I.
通讯作者：
Clyman, Ronald I.
影响因子：
1.6
作者：
Amin, S. B.;Handley, C.;Carter-Pokras, O.
通讯作者：
Carter-Pokras, O.
DOI：
10.1056/nejmoa0911781
发表时间：
2010-05-27
期刊：
The New England journal of medicine
影响因子：
--
作者：
SUPPORT Study Group of the Eunice Kennedy Shriver NICHD Neonatal Research Network;Carlo WA;Finer NN;Walsh MC;Rich W;Gantz MG;Laptook AR;Yoder BA;Faix RG;Das A;Poole WK;Schibler K;Newman NS;Ambalavanan N;Frantz ID 3rd;Piazza AJ;Sánchez PJ;Morris BH;Laroia N;Phelps DL;Poindexter BB;Cotten CM;Van Meurs KP;Duara S;Narendran V;Sood BG;O'Shea TM;Bell EF;Ehrenkranz RA;Watterberg KL;Higgins RD
通讯作者：
Higgins RD
影响因子：
3.8
作者：
Andriessen, Peter;Struis, Nicole C.;Van Overmeire, Bart
通讯作者：
Van Overmeire, Bart