Translating animal doses of task-specific training to people with chronic stroke in 1-hour therapy sessions: a proof-of-concept study.

Translating animal doses of task-specific training to people with chronic stroke in 1-hour therapy sessions: a proof-of-concept study.
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DOI:
10.1177/1545968310361957
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发表时间:
2010-09
影响因子:
4.2
通讯作者:
Lang CE
Lang CE
中科院分区:
医学1区
文献类型:
--
作者:
Birkenmeier RL;Prager EM;Lang CE

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本研究的目的是:1)在当前1小时治疗疗程的门诊提供系统范围内,检查将高重复剂量的上肢(UE)任务特定训练转化为卒中患者的可行性,以及2)收集有关这些剂量潜在获益的初步数据。15名因中风而患有慢性(> 6个月)UE轻瘫的受试者接受3周的基线评估,然后进行6周的高重复干预(3次/周,持续6周)。在每1小时的训练中,受试者被要求完成300次或更多次重复的UE功能任务训练(3项任务× 100次重复)。干预期间和干预后的评估用于衡量可行性和潜在益处。对于完成干预的13名受试者,每次会议的平均重复次数为322。参加会议的百分比为97%。受试者的疼痛和疲劳评分较低。行动研究组的测试分数在干预期间平均提高了8分,并且在1个月的随访中保持了这种提高。活动和参与的次要措施也显示出改善,而损害的措施没有。在一个小时的治疗过程中,对中风患者进行数百次重复的特定任务训练是可行的。初步结果数据表明,这种干预可能对某些中风患者有益。
The purposes of this study were to: 1) examine the feasibility of translating high repetition doses of upper extremity (UE) task-specific training to people with stroke within the confines of the current outpatient delivery system of 1 hr therapy sessions, and 2) to gather preliminary data regarding the potential benefit of these doses. Fifteen subjects with chronic (> 6 mo) UE paresis due to stroke underwent 3 weeks of baseline assessments followed by 6 weeks of the high repetition intervention (3 sessions/wk for 6 wks). During each 1 hour session, subjects were challenged to complete 300 or more repetitions of UE functional task training (3 tasks × 100 repetitions). Assessments during and after the intervention were used to measure feasibility and potential benefit. For the 13 subjects completing the intervention, the average number of repetitions per session was 322. The percentage of sessions attended was 97%. Subject ratings of pain and fatigue were low. Action Research Arm test scores improved an average of 8 points during the intervention, and the improvement was maintained at the 1 month follow-up. Secondary measures of activity and participation also showed improvement while the measure of impairment did not. It is feasible to deliver hundreds of repetitions of task-specific training to people with stroke in one hour therapy sessions. Preliminary outcome data suggest that this intervention may be beneficial for some people with stroke.
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