Early-life maternal separation and social isolation produce an increase in impulsive action but not impulsive choice.

Early-life maternal separation and social isolation produce an increase in impulsive action but not impulsive choice.
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早年与母亲的分离和社会孤立会增加冲动行为,但不会增加冲动选择。

DOI:
10.1037/a0024367
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发表时间:
2011
影响因子:
1.9
通讯作者:
A. Fleming
A. Fleming
中科院分区:
医学4区
文献类型:
--
作者:
V. Lovic;Darren Keen;P. Fletcher;A. Fleming

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早期的生活环境、事件和背景,如母子关系,会对未来的行为和生理产生深远的影响。我们调查了长期的母亲和社会分离,通过人工饲养,成年冲动的影响。大鼠由母亲饲养(MR)或人工饲养(AR)和一半的AR大鼠提供替代体感刺激,旨在模拟母亲舔。至少有2种形式的冲动,我们比较了大鼠的1个测试的冲动行为(差异强化低反应率-DRL-20)和2个测试的冲动选择(延迟折扣和固定连续数计划-FCN)。我们发现,AR大鼠的行为更冲动,然而,这种影响可以减少母亲舔样刺激。相比之下,AR大鼠的冲动选择并未增加。总的来说,这些实验表明,早期生活的母亲和社会分离对两种形式的冲动有不同的影响。
Early life environment, events, and context, such as mother-offspring relationship, can have profound effects on future behavior and physiology. We investigated the effects of long-term maternal and social separation, through artificial rearing, on adult impulsivity. Rats were maternally reared (MR) or artificially reared (AR) and half of the AR rats were provided with replacement somatosensory stimulation intended to simulate maternal licking. There are at least 2 forms of impulsivity and we compared rats on 1 test of impulsive action (differential reinforcement of low rates of responding-DRL-20s) and 2 tests of impulsive choice (delay discounting and fixed consecutive number schedule-FCN). We found that AR rats are more action impulsive; however, this effect can be reduced by maternal licking-like stimulation. In contrast, AR rats did not display an increase in impulsive choice. Overall, these experiments show that early life maternal and social separation have different effects on the 2 forms of impulsivity.
儿童期性虐待和妇女药物滥用:国家调查结果。
DOI: 10.15288/jsa.1997.58.264
发表时间: 1997
期刊: Journal of studies on alcohol
影响因子: --
作者:
Wilsnack,SC;Vogeltanz,ND;Klassen,AD;Harris,TR
通讯作者: Harris,TR
童年受害和药物滥用:前瞻性和回顾性研究结果的比较。
DOI: 10.1037//0022-006x.67.6.867
发表时间: 1999
影响因子: 5.9
作者:
Widom,CS;Weiler,BL;Cottler,LB
通讯作者: Cottler,LB