Retrograde determination of motoneuron properties and their synaptic input.
Retrograde determination of motoneuron properties and their synaptic input.
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运动神经元特性及其突触输入的逆行测定。
DOI:
10.1002/neu.480250610
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发表时间:
1994
期刊:
影响因子:
--
通讯作者:
Munson,JB
中科院分区:
文献类型:
--
作者:
Mendell,LM;Collins3rd,WF;Munson,JB
Both motoneurons and the muscle fibers that they innervate can vary widely in their properties. The finding that these properties are highly correlated indicates that these cells are not specified independently, but rather interact in some manner to achieve the observed coherence. The direction of the interaction, i.e., whether orthograde or retrograde, required analysis beyond the simple observation of these correlated properties. Evidence, largely from experiments involving reinnervation of muscle by the original or a foreign motor nerve, suggests the action of retrogradely transported factors from the muscle as well as orthograde ones. Various possible factors, specifically neurotrophins, are advanced as possible candidates for retrograde specification. In addition, synaptic input to motoneurons also varies in a coordianted fashion in a manner that suggests a retrograde determination from the muscle. However, motoneuron properties and their synaptic input change after peipheral nerve manipulations such that they are no longer in register. This indicates some independence in retrograde specification of motoneurons and their synaptic input. 1994 John Wiley & Sons, Inc.
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影响因子:
2.9
作者:
I. Araki;Y. Harada;M. Kuno
通讯作者:
M. Kuno
DOI:
10.1113/jphysiol.1976.sp011270
发表时间:
1976
期刊:
The Journal of Physiology
影响因子:
--
作者:
L. Mendell;J. Munson;J. G. Scott
通讯作者:
J. G. Scott
DOI:
--
发表时间:
1974
期刊:
影响因子:
--
作者:
M. Kuno;Y. Miyata;E. Muñoz‐Martinez
通讯作者:
E. Muñoz‐Martinez
影响因子:
2.5
作者:
VandenNoven,S;Pinter,MJ
通讯作者:
Pinter,MJ
影响因子:
2.5
作者:
DUM, RP;ODONOVAN, MJ;BURKE, RE
通讯作者:
BURKE, RE