Comparison of setup accuracy of optical surface image versus orthogonal x-ray images for VMAT of the left breast using deep-inspiration breath-hold.

Comparison of setup accuracy of optical surface image versus orthogonal x-ray images for VMAT of the left breast using deep-inspiration breath-hold.
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DOI:
10.1002/acm2.14117
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发表时间:
2023-12
影响因子:
2.1
通讯作者:
Li, Guang
Li, Guang
中科院分区:
医学4区
文献类型:
--
作者:
Lu, Wei;Hong, Linda X.;Yamada, Nelson;Berry, Sean L.;Song, Yulin;Choi, Wookjin;Cervino, Laura I.;Tang, Xiaoli;Mechalakos, James G.;Romesser, Paul B.;Powell, Simon;Li, Guang

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比较光学表面图像(OSI)与正交X射线图像(2DkV)的设置准确性,使用锥形束计算机断层扫描(CBCT)作为深吸气屏气(DIBH)下左乳腺癌放疗的基础事实。回顾性研究了10例左乳DIBH患者接受体积调制式弧形治疗(VMAT)。在治疗设置时每周采集一次OSI、2DkV和CBCT。OSI、2DkV和CBCT分别基于乳房表面感兴趣区域(ROI)、骨性解剖结构(胸壁和胸骨)以及骨性解剖结构和乳房表面配准到计划CT或计划DRR。这些配准为每个成像系统提供治疗床移位。将OSI和CBCT之间的摆位误差或治疗床移位差异与2DkV和CBCT之间的摆位误差或治疗床移位差异进行比较。在最后一次射束输送期间采集第二次OSI,以评估分次内运动。在垂直、纵向和横向平移以及旋转、滚动和俯仰方面,OSI和2DkV的中位绝对摆位误差分别为(0.21、0.27、0.23 cm、0.6°、1.3°、1.0°)和(0.26、0.24、0.18 cm、0.9°、1.0°、0.6°)。OSI和2DkV之间的设置误差无显著差异。对于两种系统,系统和随机设置误差在所有方向上均≤0.6 cm和≤1.5°。然而,在两个系统的某些会话中观察到较大的设置误差。OSI和CBCT之间没有相关性,而2DkV和CBCT之间有一定的相关性。通过OSI检测到的DIBH的分次内运动较小,平均绝对平移<0.2 cm,旋转≤0.4°。尽管OSI显示与2DkV相当且较小的设置误差,但它与CBCT没有相关性。我们得出结论,为了实现骨骼解剖结构和乳房表面的准确设置,对于接受DIBH VMAT治疗的左乳房患者,在OSI后不能省略每日2DkV。
To compare the setup accuracy of optical surface image (OSI) versus orthogonal x‐ray images (2DkV) using cone beam computed tomography (CBCT) as ground truth for radiotherapy of left breast cancer in deep‐inspiration breath‐hold (DIBH). Ten left breast DIBH patients treated with volumetric modulated arc therapy (VMAT) were studied retrospectively. OSI, 2DkV, and CBCT were acquired weekly at treatment setup. OSI, 2DkV, and CBCT were registered to planning CT or planning DRR based on a breast surface region of interest (ROI), bony anatomy (chestwall and sternum), and both bony anatomy and breast surface, respectively. These registrations provided couch shifts for each imaging system. The setup errors, or the difference in couch shifts between OSI and CBCT were compared to those between 2DkV and CBCT. A second OSI was acquired during last beam delivery to evaluate intrafraction motion. The median absolute setup errors were (0.21, 0.27, 0.23 cm, 0.6°, 1.3°, 1.0°) for OSI, and (0.26, 0.24, 0.18 cm, 0.9°, 1.0°, 0.6°) for 2DkV in vertical, longitudinal and lateral translations, and in rotation, roll and pitch, respectively. None of the setup errors was significantly different between OSI and 2DkV. For both systems, the systematic and random setup errors were ≤0.6 cm and ≤1.5° in all directions. Nevertheless, larger setup errors were observed in some sessions in both systems. There was no correlation between OSI and CBCT whereas there was modest correlation between 2DkV and CBCT. The intrafraction motion in DIBH detected by OSI was small with median absolute translations <0.2 cm, and rotations ≤0.4°. Though OSI showed comparable and small setup errors as 2DkV, it showed no correlation with CBCT. We concluded that to achieve accurate setup for both bony anatomy and breast surface, daily 2DkV can't be omitted following OSI for left breast patients treated with DIBH VMAT.
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