Oral feeding options for people with dementia: a systematic review.

Oral feeding options for people with dementia: a systematic review.
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DOI:
10.1111/j.1532-5415.2011.03320.x
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发表时间:
2011-03
影响因子:
6.3
通讯作者:
Carey TS
Carey TS
中科院分区:
医学1区
文献类型:
--
作者:
Hanson LC;Ersek M;Gilliam R;Carey TS

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大多数痴呆症患者会出现喂养问题,导致医生和家庭考虑管饲或口服喂养。管饲提供有限的好处,但目前的决策包括有限的信息,其他选择。回顾痴呆症患者口服喂养选择的证据。系统评价。PubMed/MEDLINE、EMBASE、科克伦图书馆、CINAHL和PsychINFO文献索引,1990年1月至2009年10月。如果随机或非随机对照组的临床试验报告了痴呆患者口服喂养干预的临床结局,则将其纳入。系统性文献检索,由两名独立研究者对潜在合格研究进行审查。研究者使用结构化工具从纳入的研究中提取数据。对研究的质量和潜在偏倚进行分级,并总结总体证据强度。13项对照试验提供了痴呆患者使用补充剂的数据,12项对照试验测试了辅助喂养或其他干预措施。研究为高热量补充剂提供了中等强度的证据,为食欲刺激剂、辅助喂养和改良食品提供了低强度的证据,以促进痴呆症患者的体重增加。少数测量功能或存活率的研究显示没有差异。高热量补充剂和其他口服喂养选择可以帮助有喂养问题的痴呆症患者增加体重;它们不太可能改善其他结果。这些治疗可以单独或组合提供,作为管饲的替代方案。
Most patients with dementia develop feeding problems, leading physicians and families to consider tube feeding or oral feeding options. Tube feeding offers limited benefit, but current decision-making includes limited information on other options. To review the evidence for oral feeding options in dementia. Systematic review. PubMed/MEDLINE, EMBASE, the Cochrane Library, CINAHL and PsychINFO literature indices between January 1990 and October 2009. Clinical trials with random or non-random control groups were included if they reported on clinical outcomes of oral feeding interventions for patients with dementia. Systematic literature search with review of potentially eligible studies by two independent investigators. Investigators abstracted data from included studies using a structured instrument. Studies were graded on quality and potential bias, and overall strength of evidence summarized. Thirteen controlled trials provide data on use of supplements for patients with dementia, and twelve controlled trials test assisted feeding or other interventions. Studies provide moderate strength evidence for high calorie supplements, and low strength evidence for appetite stimulants, assisted feeding and modified foods to promote weight gain in dementia. The few studies measuring function or survival showed no difference. High calorie supplements and other oral feeding options can help dementia patients with feeding problems to gain weight; they are unlikely to improve other outcomes. These treatments can be offered alone or in combination as an alternative to tube feeding.
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