Foodborne Campylobacter: infections, metabolism, pathogenesis and reservoirs.

Foodborne Campylobacter: infections, metabolism, pathogenesis and reservoirs.
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DOI:
10.3390/ijerph10126292
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发表时间:
2013-11-26
影响因子:
--
通讯作者:
Nisbet DJ
Nisbet DJ
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Epps SV;Harvey RB;Hume ME;Phillips TD;Anderson RC;Nisbet DJ

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弯曲杆菌是世界范围内细菌源性食源性疾病的主要原因。这种细菌群作为人类疾病的重要病原体的出现,以及它们携带抗生素耐药元素的倾向,使它们能够抵抗抗菌治疗,使它们成为严重的公共卫生威胁。空肠弯曲杆菌(Campylobacter jejuni)和大肠弯曲杆菌(Campylobacter coli)被认为是该属中最重要的肠致病菌,它们在各种动物物种和栖息地中定植和生存的能力使它们极难控制。本文回顾了这一细菌群的历史和新兴的重要性,并讨论了它们引起的人类感染,它们的代谢和发病机制,以及它们的天然宿主,以便解决适当的食品安全法规和干预措施的需要。
Campylobacter species are a leading cause of bacterial-derived foodborne illnesses worldwide. The emergence of this bacterial group as a significant causative agent of human disease and their propensity to carry antibiotic resistance elements that allows them to resist antibacterial therapy make them a serious public health threat. Campylobacter jejuni and Campylobacter coli are considered to be the most important enteropathogens of this genus and their ability to colonize and survive in a wide variety of animal species and habitats make them extremely difficult to control. This article reviews the historical and emerging importance of this bacterial group and addresses aspects of the human infections they cause, their metabolism and pathogenesis, and their natural reservoirs in order to address the need for appropriate food safety regulations and interventions.
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发表时间: 2002-03
影响因子: 11.8
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