Predictive Effect of Intervertebral Foramen Width on Pain Relief After ACDF for the Treatment of Cervical Radiculopathy.

Predictive Effect of Intervertebral Foramen Width on Pain Relief After ACDF for the Treatment of Cervical Radiculopathy.
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椎间孔宽度对 ACDF 治疗神经根型颈椎病后疼痛缓解的预测作用。

DOI:
10.1177/2192568221993444
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发表时间:
2023-01
影响因子:
2.4
通讯作者:
Liu, Yang
Liu, Yang
中科院分区:
医学4区
文献类型:
--
作者:
Sun, Baifeng;Xu, Chen;Qi, Min;Shen, Xiaolong;Zhang, Ke;Yuan, Wen;Liu, Yang

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回顾性队列研究。探讨术前椎间孔宽度(WIVF)与颈前路椎间盘切除融合术(ACDF)治疗神经根型颈椎病患者疼痛缓解的关系。根据6个月随访时的疼痛缓解状态将患者分为2组(疼痛缓解组:430例患者;持续性疼痛组:108例患者)。获得了可能的因素,如年龄、性别、体重指数(BMI)、症状持续时间、术前日本骨科协会(乔亚)评分、椎管狭窄状态和移植材料。在X线片和CT三维重建上测量C2 ~ C7 Cobb角、椎间隙、椎间孔宽度和高度。进行多变量逻辑回归以确定影响疼痛缓解的因素。绘制受试者工作特征(ROC)曲线,以确定预测持续性疼痛的最佳阈值。两组术前WIVF、症状持续时间及椎间隙牵张率比较差异均有统计学意义(均P < 0.05)。回归模型显示疼痛缓解受症状持续时间和椎间隙牵张比例的负面影响。此外,增加术前椎间孔宽度(WIVF)可显著降低持续性疼痛的可能性。根据ROC曲线,术前WIVF的最佳阈值为4.35 mm。当术前WIVF等于或小于4.35 mm时,发生术后持续性疼痛的可能性明显增加。
Retrospective cohort study. To investigate the relationship between the preoperative width of the intervertebral foramen (WIVF) and the pain relief in patients who underwent anterior cervical discectomy and fusion (ACDF) for the treatment of cervical radiculopathy. Patients were divided into 2 groups based on pain relief status at the 6-month follow-up (pain relief group: 430 patients; persistent pain group: 108 patients). Possible factors such as age, sex, body mass index (BMI), the symptom duration, the preoperative Japanese Orthopedic Association (JOA) scores, the canal stenosis status, and the graft material were obtained. The C2-C7 Cobb angle, disc space, and width and height of the intervertebral foramen were measured on X-ray and CT 3-dimension reconstruction. Multivariate logistic regression was performed to identify the factors that affected pain relief. A receiver operating characteristic (ROC) curve was drawn for the predictive factors to determine the optimal threshold for foreseeing persistent pain. There were significant differences in the preoperative WIVF, symptom duration and ratio of disc space distraction between the 2 groups (each P < 0.05). The regression model showed that pain relief was negatively affected by the symptom duration and ratio of disc space distraction. Besides, an increase in the preoperative width of the intervertebral foramen (WIVF) could significantly decrease the possibility of persistent pain. Based on the ROC curve, the optimal threshold of preoperative WIVF was 4.35 mm. When the preoperative WIVF is equal to or less than 4.35 mm, the possibility of the occurrence of postoperative persistent pain significantly increased.
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