Outcomes of Pregnancies and Deliveries of Patients Who Underwent Fertility-Preserving Surgery for Early-Stage Epithelial Ovarian Cancer.
Outcomes of Pregnancies and Deliveries of Patients Who Underwent Fertility-Preserving Surgery for Early-Stage Epithelial Ovarian Cancer.
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DOI：
10.3390/jcm11185346
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发表时间：
2022-09-12
影响因子：
3.9
通讯作者：
Yaegashi N
中科院分区：
文献类型：
--
作者：
Nishio S;Takeno T;Fukuda T;Shikama A;Nakai H;Nakamura H;Tokunaga H;Takahashi K;Okuma E;Mori M;Terao Y;Ushijima K;Yaegashi N
一些研究表明，在肿瘤治疗后，早产、低出生体重和剖腹产的风险增加；另一些研究则显示相反。我们评估了接受早期上皮性卵巢癌(EOC)保留生育手术(FSS)的患者的妊娠和分娩结果，并检查了他们的围产儿预后。这项回顾性研究包括我们先前研究中报告的IA或IC期卵巢癌病史的妇女。在考虑癌症诊断后，主要结果是早产。次要结果是新生儿发病率和严重的产妇发病率。25名接受过FSS手术的妇女共生育了31个孩子。平均分娩周38.7±0.7周，新生儿平均出生体重3021±160g，早产5例，足月分娩26例。分娩方式：阴道分娩18例，剖宫产13例。妊娠期并发症包括前置胎盘和盆腔脓肿各1例。除3例早产儿低出生体重儿外，无其他围产期异常。尽管剖宫产率较高，但EOC保留生育能力后妊娠的围产儿预后良好。
Some studies have shown increased risks of preterm birth, low birth weight, and cesarean delivery after oncologic treatment; others have shown the opposite. We evaluated the outcomes of pregnancies and deliveries of patients who underwent fertility-preserving surgery (FSS) for early-stage epithelial ovarian cancer (EOC) and examined their perinatal prognosis. This retrospective study included women with a history of stage IA or IC ovarian cancer reported in our previous study. The primary outcome was preterm birth after cancer diagnosis was considered. Secondary outcomes were neonatal morbidity and severe maternal morbidity. Thirty-one children were born to 25 women who had undergone FSS. The mean number of weeks at delivery was 38.7 ± 0.7, and the mean birth weight of infants was 3021 ± 160 g. With respect to pregnancy outcomes, 5 patients had preterm labor and 26 had full-term labor. The delivery mode was vaginal delivery in 18 patients and cesarean delivery in 13. Complications during pregnancy included placenta previa (one case) and pelvic abscess (one case). Except for three preterm infants with low birth weight, there were no other perinatal abnormalities. Pregnancy after fertility preservation in EOC has an excellent perinatal prognosis, although the cesarean delivery rate is high.
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影响因子：
3.8
作者：
Johansen G;Dahm-Kähler P;Staf C;Flöter Rådestad A;Rodriguez-Wallberg KA
通讯作者：
Rodriguez-Wallberg KA
影响因子：
3.7
作者：
Haggar FA;Pereira G;Preen D;Holman CD;Einarsdottir K
通讯作者：
Einarsdottir K
影响因子：
51.1
作者：
Chow, Eric J.;Stratton, Kayla L.;Green, Daniel M.
通讯作者：
Green, Daniel M.
影响因子：
50.5
作者：
Fruscio, R.;Corso, S.;Colombo, N.
通讯作者：
Colombo, N.
DOI：
10.1093/jnci/djx056
发表时间：
2017-11-01
期刊：
Journal of the National Cancer Institute
影响因子：
--
作者：
Reulen RC;Bright CJ;Winter DL;Fidler MM;Wong K;Guha J;Kelly JS;Frobisher C;Edgar AB;Skinner R;Wallace WHB;Hawkins MM
通讯作者：
Hawkins MM