Real-Time Emulator for Reproducing Graded Potentials in Vertebrate Retina

Real-Time Emulator for Reproducing Graded Potentials in Vertebrate Retina
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用于再现脊椎动物视网膜分级电位的实时模拟器

DOI:
10.1109/tbcas.2014.2327103
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发表时间:
2015
影响因子:
5.1
通讯作者:
奥野弘嗣,長谷川潤,八木哲也
奥野弘嗣,長谷川潤,八木哲也
中科院分区:
工程技术2区
文献类型:
--
作者:
奥野弘嗣,長谷川潤,八木哲也

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在视网膜的大部分区域中,神经元回路处理由缓慢变化的膜电位或所谓的分级电位表示的视觉信号。一个可行的方法来推测视网膜神经元回路的功能作用是再现视网膜神经元对自然场景的分级电位。在这项研究中,我们开发了一个仿真平台,用于再现分级电位具有以下特点:实时再现视网膜神经活动,以响应自然场景,可配置的模型结构,和紧凑的硬件。采用模拟电阻网络和现场可编程门阵列组成的模拟-数字混合结构,有效地模拟了神经元的时空特性。在持续和短暂的路径上的神经活动,从128128输入,以200帧每秒的仿真。
In most parts of the retina, neuronal circuits process visual signals represented by slowly changing membrane potentials, or so-called graded potentials. A feasible approach to speculate about the functional roles of retinal neuronal circuits is to reproduce the graded potentials of retinal neurons in response to natural scenes. In this study, we developed a simulation platform for reproducing graded potentials with the following features: real-time reproduction of retinal neural activities in response to natural scenes, a configurable model structure, and compact hardware. The spatio-temporal properties of neurons were emulated efficiently by a mixed analog-digital architecture that consisted of analog resistive networks and a field-programmable gate array. The neural activities on sustained and transient pathways were emulated from 128128 inputs at 200 frames per second.
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