Dynamic coding of signed quantities in cortical feedback circuits.
Dynamic coding of signed quantities in cortical feedback circuits.
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DOI：
10.3389/fpsyg.2012.00254
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发表时间：
2012
影响因子：
3.8
通讯作者：
Jehee J
中科院分区：
文献类型：
--
作者：
Ballard DH;Jehee J
在皮层的早期感觉和运动区域，单个神经元通过峰值反应传递有关特定感觉特征的信息。这个概念被具体化为“标记线”，表示轴突传达其感觉或运动母细胞的特定属性。此类单元还可以被表征为极化的，即，代表正或负的有符号量。我们在模型模拟中表明，在减去不同输入的电路中使用此类符号编码来学习感受野时，会产生两个重要后果。首先，在使用标记线的反馈电路中，此类算术运算需要分布在多个不同的路径上。第二个结果是，这样的通路必须是动态的，即突触在形成感受野时可以生长和收缩。当突触需要改变极性时，该模型会监测新电路连接的断开和生长，并预测这种变化的速率应与感受野形成的进度成反比。
In the early sensory and motor areas of the cortex, individual neurons transmit information about specific sensory features via a peaked response. This concept has been crystallized as “labeled lines,” to denote that axons communicate the specific properties of their sensory or motor parent cell. Such cells also can be characterized as being polarized, that is, as representing a signed quantity that is either positive or negative. We show in a model simulation that there are two important consequences when learning receptive fields using such signed codings in circuits that subtract different inputs. The first is that, in feedback circuits using labeled lines, such arithmetic operations need to be distributed across multiple distinct pathways. The second consequence is that such pathways must be necessarily dynamic, i.e., that synapses can grow and retract when forming receptive fields. The model monitors the breaking and growing of new circuit connections when their synapses need to change polarities and predicts that the rate of such changes should be inversely correlated with the progress of receptive field formation.
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影响因子：
3.2
作者：
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