Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury.

Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury.
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DOI:
10.1186/cc5713
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发表时间:
2007
期刊:
Critical care (London, England)
影响因子:
--
通讯作者:
Acute Kidney Injury Network
Acute Kidney Injury Network
中科院分区:
其他
文献类型:
--
作者:
Mehta RL;Kellum JA;Shah SV;Molitoris BA;Ronco C;Warnock DG;Levin A;Acute Kidney Injury Network

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急性肾损伤(阿基)是一种复杂的疾病,目前还没有公认的定义。有一个诊断和分类阿基的统一标准将提高我们管理这些患者的能力。未来阿基的临床和转化研究将需要来自不同学科的研究者合作网络,通过多学科联合会议和出版物传播信息,并改善临床前研究知识的转化。我们描述了一项倡议,旨在制定阿基定义和分类的统一标准,并建立一个多学科互动的论坛,以改善对AKI患者或有阿基风险患者的护理。沿着代表重症监护和肾脏病学主要学会的成员以及成人和儿科阿基的其他专家于2005年9月在荷兰阿姆斯特丹参加了为期两天的会议,并被分配到三个工作组之一。每个小组的讨论构成了建议草案的基础,这些建议草案后来在与更大小组的讨论中得到了完善和改进。也注意到了不同意见。最后的建议草案已分发给所有与会者,随后商定作为本报告的协商一致建议。与会学会赞同这些建议,并同意帮助传播结果。术语阿基被提议代表急性肾衰竭的整个谱。阿基的诊断标准是基于血清肌酐或尿量的急性变化。已经开发了阿基的分期系统,其反映了血清肌酐和尿量的定量变化。我们描述了一个多学科协作网络的形成,专注于阿基。我们已经提出了诊断和分类阿基的统一标准,需要在未来的研究中进行验证。急性肾损伤网络提供了一个机制,继续努力,以改善患者的结果。
Acute kidney injury (AKI) is a complex disorder for which currently there is no accepted definition. Having a uniform standard for diagnosing and classifying AKI would enhance our ability to manage these patients. Future clinical and translational research in AKI will require collaborative networks of investigators drawn from various disciplines, dissemination of information via multidisciplinary joint conferences and publications, and improved translation of knowledge from pre-clinical research. We describe an initiative to develop uniform standards for defining and classifying AKI and to establish a forum for multidisciplinary interaction to improve care for patients with or at risk for AKI. Members representing key societies in critical care and nephrology along with additional experts in adult and pediatric AKI participated in a two day conference in Amsterdam, The Netherlands, in September 2005 and were assigned to one of three workgroups. Each group's discussions formed the basis for draft recommendations that were later refined and improved during discussion with the larger group. Dissenting opinions were also noted. The final draft recommendations were circulated to all participants and subsequently agreed upon as the consensus recommendations for this report. Participating societies endorsed the recommendations and agreed to help disseminate the results. The term AKI is proposed to represent the entire spectrum of acute renal failure. Diagnostic criteria for AKI are proposed based on acute alterations in serum creatinine or urine output. A staging system for AKI which reflects quantitative changes in serum creatinine and urine output has been developed. We describe the formation of a multidisciplinary collaborative network focused on AKI. We have proposed uniform standards for diagnosing and classifying AKI which will need to be validated in future studies. The Acute Kidney Injury Network offers a mechanism for proceeding with efforts to improve patient outcomes.
急性肾脏损伤的步枪标准与重症患者的医院死亡率有关:一项队列分析。
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期刊: CRITICAL CARE
影响因子: 15.1
作者:
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发表时间: 2003-08-01
影响因子: 13.6
作者:
Mehta, RL;Chertow, GM
通讯作者: Chertow, GM
DOI: 10.1097/01.ccm.0000182798.39709.84
发表时间: 2005-10-01
影响因子: 8.8
作者:
Levy, MM;Macias, WL;Williams, MD
通讯作者: Williams, MD