Regulatory Role of MicroRNAs in Muscle Atrophy during Exercise Intervention.

Regulatory Role of MicroRNAs in Muscle Atrophy during Exercise Intervention.
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MicroRNA 在运动干预期间肌肉萎缩中的调节作用。

DOI:
10.3390/ijms19020405
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发表时间:
2018-01-30
影响因子:
5.6
通讯作者:
Chen N
Chen N
中科院分区:
生物学2区
文献类型:
--
作者:
Zhang S;Chen N

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Skeletal muscle comprising approximately 40% of body weight is highly important for locomotion and metabolic homeostasis. The growth and regeneration of skeletal muscle are highly organized processes; thus, it is not surprising to reveal certain complexity during these regulatory processes. Recently, a large number of evidence indicate that microRNAs can result in obvious impacts on growth, regeneration and metabolism of skeletal muscle. In this review, recent research achievements of microRNAs in regulating myogenesis, atrophy and aging during exercise intervention are discussed, which will provide the guidance for developing potential applications of microRNAs in health promotion and rehabilitation of sports injuries.
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