Continuous control of blood glucose in TIDM using fuzzy logic controller in insulin pump: A simulation study

Continuous control of blood glucose in TIDM using fuzzy logic controller in insulin pump: A simulation study
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使用胰岛素泵中的模糊逻辑控制器连续控制 TIDM 中的血糖:模拟研究

DOI:
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发表时间:
2011
期刊:
International Conference on Computer and Information Application
影响因子:
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通讯作者:
A. Geramipour
A. Geramipour
中科院分区:
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文献类型:
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作者:
A. Maleki;A. Geramipour

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本文介绍了一种用于调节1型糖尿病患者血糖水平的闭环控制系统。控制器设计的目标是1.避免低血糖(血糖浓度应高于3 mmol/l)和2.降低糖尿病患者的血糖水平(平均血糖应低于7 mmol/l)。通过模拟健康人的自然胰岛素分泌的连续皮下胰岛素输注泵描述了对这些患者的强化治疗。控制算法使用医生的经验来治疗这种疾病,通过使用Mamdani型模糊逻辑控制器(FLC)。通过一组糖尿病患者模型验证了该控制器的鲁棒性。然后评估模糊控制器的性能和能力,FLC的结果进行了比较,PID控制器为每个糖尿病患者。结果表明,FLC在系统参数存在不确定性的情况下具有更稳定的响应,这些不确定性可能因患者而异。
This paper presents a closed-loop control system for regulating blood glucose level in type-1 diabetic patients. The goals of designing controller are 1. avoidance of hypoglycemia (blood glucose concentrations should be above 3mmol/l) and 2. reduction in the blood glucose level (average blood glucose should be less than 7mmol/l) in diabetic patients. An intensive therapy for these patients is described by a continuous subcutaneous insulin infusion pump which mimics the natural insulin secretion in healthy person. The control algorithm uses experience of physicians to treat this disease by using Mamdani-type fuzzy logic controller (FLC). Robustness of this controller is tested by a group of diabetic patients models. Then to assess the performance and capabilities of fuzzy controller, the results of FLC were compared to PID controller for each diabetic patient. The results showed that FLC has a more stable response in presence of uncertainty in system parameters which can vary from patient to patient.
DOI: 10.1172/jci110398
发表时间: 1981-01-01
影响因子: 15.9
作者:
BERGMAN, RN;PHILLIPS, LS;COBELLI, C
通讯作者: COBELLI, C
DOI: 10.1016/0169-2607(86)90106-9
发表时间: 1986-10-01
影响因子: 6.1
作者:
PACINI, G;BERGMAN, RN
通讯作者: BERGMAN, RN