Specific enrichment methods for glycoproteome research
Specific enrichment methods for glycoproteome research
复制标题
糖蛋白质组研究的具体富集方法
DOI:
10.1007/s00216-009-3086-0
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发表时间:
2010
期刊:
影响因子:
--
通讯作者:
Zhang, Lijuan
中科院分区:
文献类型:
--
作者:
Lu, Haojie;Yang, Pengyuan;Zhang, Lijuan
Glycosylation is, by far, one of the most common and important post-translational modifications and becomes a target for proteomic research. A key challenge in glycoproteome research is the development of fast and effective enrichment strategies for high-throughput glycosylation analysis. Different kinds of glycan-capturing anchors have been developed and successfully applied to glyco-specific enrichment in large-scale glycosylation identification in the past few years. In this paper, we highlight several examples on various types of enrichment methods that have been utilized to specifically capture glycopeptides/glycoproteins for subsequent mass spectrometric analysis.
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