Epigenetic considerations in aquaculture.
Epigenetic considerations in aquaculture.
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作者：
Gavery MR;Roberts SB
表观遗传学因其在农业生产许多领域的潜在价值而引起了相当大的关注，特别是在环境可以操纵或存在自然变异的条件下。在这里，我们介绍了表观遗传学机制的关键概念和定义，包括DNA甲基化、组蛋白修饰和非编码RNA，回顾了目前对鱼类和贝类表观遗传学的理解，并提出了表观遗传学可以应用的水产养殖的关键领域。第一个关键领域是环境操纵，其目的是在代内或代际之间诱导“表观遗传记忆”，以产生所需的表型。第二个关键领域是表观遗传选择，它单独或与遗传选择相结合，可以提高生产具有所需表型的动物的可靠性。根据水产养殖物种的生活史和饲养实践，表观遗传知识的应用可以显着影响水产养殖实践的生产力和可持续性。相反，阐明表观遗传机制在水产养殖物种中的作用可能会颠覆有关选择实践的传统假设。最终，关于如何在水产养殖中利用表观遗传机制，仍有许多悬而未决的问题。
Epigenetics has attracted considerable attention with respect to its potential value in many areas of agricultural production, particularly under conditions where the environment can be manipulated or natural variation exists. Here we introduce key concepts and definitions of epigenetic mechanisms, including DNA methylation, histone modifications and non-coding RNA, review the current understanding of epigenetics in both fish and shellfish, and propose key areas of aquaculture where epigenetics could be applied. The first key area is environmental manipulation, where the intention is to induce an ‘epigenetic memory’ either within or between generations to produce a desired phenotype. The second key area is epigenetic selection, which, alone or combined with genetic selection, may increase the reliability of producing animals with desired phenotypes. Based on aspects of life history and husbandry practices in aquaculture species, the application of epigenetic knowledge could significantly affect the productivity and sustainability of aquaculture practices. Conversely, clarifying the role of epigenetic mechanisms in aquaculture species may upend traditional assumptions about selection practices. Ultimately, there are still many unanswered questions regarding how epigenetic mechanisms might be leveraged in aquaculture.
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影响因子：
4.4
作者：
Andreassen R;Woldemariam NT;Egeland IØ;Agafonov O;Sindre H;Høyheim B
通讯作者：
Høyheim B
DOI：
10.1038/nrg3355
发表时间：
2013-02
期刊：
Nature reviews. Genetics
影响因子：
--
作者：
通讯作者：
--
影响因子：
3.3
作者：
Bizuayehu TT;Babiak I
通讯作者：
Babiak I
影响因子：
16.8
作者：
Brykczynska, Urszula;Hisano, Mizue;Peters, Antoine H. F. M.
通讯作者：
Peters, Antoine H. F. M.
影响因子：
16.8
作者：
Buschbeck, Marcus;Uribesalgo, Iris;Di Croce, Luciano
通讯作者：
Di Croce, Luciano