Prevalence of ischaemic ECG abnormalities according to the diabetes status in the population of Fiji and their associations with other risk factors.

Prevalence of ischaemic ECG abnormalities according to the diabetes status in the population of Fiji and their associations with other risk factors.
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根据斐济人群的糖尿病状况,缺血性心电图异常的患病率及其与其他危险因素的关联。

DOI:
10.1016/s0168-8227(88)80090-1
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发表时间:
1988
影响因子:
5.1
通讯作者:
Ram,P
Ram,P
中科院分区:
医学3区
文献类型:
--
作者:
Tuomilehto,J;Zimmet,P;Kankaanpää,J;Wolf,E;Hunt,D;King,H;Ram,P

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对居住在斐济的美拉尼西亚人(444名男子和457名妇女)和亚洲印度人(408名男子和435名妇女)中表明存在冠心病的心电图异常的患病率进行了检查。本分析的目的是确定糖尿病、糖耐量受损(IGT)或糖耐量正常人群中冠状动脉危险因素的水平。提示冠心病的心电图异常(Q波、ST段压低或T波改变)的患病率,女性高于男性,亚裔印度人高于美拉尼西亚人。ECG异常的患病率在糖尿病受试者中最高,在IGT人群中居中,在糖耐量正常人群中最低。IGT患者比其他人更有可能具有高风险因素水平。与糖耐量正常的人群相比,IGT人群中其他冠状动脉危险因素水平的增加可能解释了ECG异常患病率的增加。同样在糖尿病受试者中,其他冠状动脉危险因素的水平在ECG异常的受试者中增加,但不超过IGT的情况,因此糖尿病本身似乎仍然是ECG异常的主要确定危险因素。在我们的研究人群中,糖尿病的患病率非常高,特别是在亚洲印度人中。这表明糖尿病是这些人群中冠心病的主要危险因素。
The prevalence of ECG abnormalities indicating the presence of coronary heart disease was examined in the Melanesian (444 men and 457 women) and Asian Indian (408 men and 435 women) population living in Fiji. The aim of the present analysis was to determine the levels of coronary risk factors in people with diabetes, impaired glucose tolerance (IGT) or normal glucose tolerance. The prevalence of ECG abnormalities suggesting coronary heart disease (Q-waves, ST-depression or T-wave changes) was higher among women than men and among Asian Indians than Melanesians. The prevalence of ECG abnormalities was highest in diabetic subjects, intermediate in people with IGT and lowest in people who had normal glucose tolerance. People with IGT were more likely than others to have high risk factor levels. In people with IGT the increased levels of other coronary risk factors might explain a great deal of the increased prevalence of the ECG abnormalities as compared with the prevalence in those with normal glucose tolerance. Also in diabetic subjects, the levels of other coronary risk factors were increased in those who had ECG abnormalities, but not more than was the case with IGT, so that diabetes itself seemed to remain as the major identified risk factor for ECG abnormalities. The prevalence of diabetes in our study populations, especially in Asian Indians, was very high. This suggests that diabetes is the major risk factor for coronary heart disease in such populations.
DOI: 10.1001/archinte.1971.00310240083010
发表时间: 1971
影响因子: 39
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