Is the microagglutination test (MAT) good for predicting the infecting serogroup for leptospirosis in Brazil?

Is the microagglutination test (MAT) good for predicting the infecting serogroup for leptospirosis in Brazil?
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微凝集测试(MAT)是否有助于预测巴西钩端螺旋体病的感染血清群?

DOI:
10.1016/j.cimid.2015.12.003
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发表时间:
2016-02
期刊:
Comparative immunology, microbiology and infectious diseases
影响因子:
--
通讯作者:
Romero EC
Romero EC
中科院分区:
其他
文献类型:
--
作者:
Blanco RM;dos Santos LF;Galloway RL;Romero EC

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钩端螺旋体病是一种由钩端螺旋体属致病性成员引起的人畜共患感染。了解流行的血清型及其维持宿主对了解该病至关重要。本研究的目的是评价显微镜凝集试验(MAT)的血清学预测血清群的能力,并与巴西圣保罗的钩端螺旋体鉴定结果进行比较。49/52例(94.23%)感染分离物的血清组正确划分。以黄疸型出血为主(88.46%)。这项研究表明,MAT在正确识别感染血清组方面的有效性,在血清学鉴定的感染血清组和分离物鉴定之间具有良好的总体一致性,可用于<s:1>圣保罗市的流行病学调查。然而,它应该辅以钩端螺旋体分离物的鉴定。
Leptospirosis is a zoonotic infection caused by pathogenic members of the genus Leptospira spp. Knowledge of the prevalent serovars and their maintenance hosts is essential to understand the disease. The aim of this study was to evaluate the ability of serology by the microscopic agglutination test (MAT) to predict the serogroups compared with results of identification of leptospires in São Paulo, Brazil. MAT correctly assigned the serogroup of the infecting isolate in 49/52 cases (94.23%). The serogroup Ictero-haemorrhagiae was the predominant serogroup (88.46%). This study showed the usefulness of the MAT to correctly identify the infecting serogroup with a good overall agreement between the serologically-identified infecting serogroup and by identification of the isolate and can be used in epidemiological surveys in São Paulo. However, it should be complemented by the identification of Leptospira isolates.
DOI: 10.1111/j.1472-765x.2009.02580.x
发表时间: 2009-05-01
影响因子: 2.4
作者:
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发表时间: 2011-11-01
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