Class-specific antibody response to pneumococcal capsular polysaccharides in men infected with human immunodeficiency virus type 1.
Class-specific antibody response to pneumococcal capsular polysaccharides in men infected with human immunodeficiency virus type 1.
复制标题
感染 1 型人类免疫缺陷病毒的男性对肺炎球菌荚膜多糖的类别特异性抗体反应。
DOI:
--
复制
发表时间:
1988
影响因子:
6.4
通讯作者:
F. N. Judson
中科院分区:
文献类型:
--
作者:
E. N. Janoff;John M. Douglas;Mark Gabriel;Martin J. Blaser;Arthur J. Davidson;David L. Cohn;F. N. Judson
We characterized the effect of infection with human immunodeficiency virus type 1 (HIV) on levels of total immunoglobulins and pneumococcal vaccine-specific immunoglobulins in 28 heterosexual and 25 homosexual men seronegative for HIV; 27 asymptomatic, seropositive homosexual men; and 21 patients with AIDS. Total serum IgG levels were increased in both HIV-seropositive groups compared with the HIV-seronegative men (P less than .001). Total IgM levels, however, were elevated only in the asymptomatic, HIV-seropositive men (P less than .08); total IgA levels were elevated only in the patients with AIDS (P less than .05). Vaccine-specific serum IgG, IgM, and IgA significantly increased over baseline three and six weeks after immunization in all groups (P less than .05). Responses to vaccine among the HIV-seronegative groups were similar but were greater for all antibody classes than were responses among the HIV-seropositive groups (P less than .05).
登录
查看更多内容
影响因子:
9.1
作者:
Ochs,HD;Junker,AK;Collier,AC;Virant,FS;Handsfield,HH;Wedgwood,RJ
通讯作者:
Wedgwood,RJ
影响因子:
4.6
作者:
Mizuma,H;Zolla-Pazner,S;Litwin,S;el-Sadr,W;Sharpe,S;Zehr,B;Weiss,S;Saxinger,WC;Marmor,M
通讯作者:
Marmor,M
DOI:
--
发表时间:
1987
期刊:
JAMA
影响因子:
--
作者:
Huang,KL;Ruben,FL;RinaldoJr,CR;Kingsley,L;Lyter,DW;Ho,M
通讯作者:
Ho,M
DOI:
10.1016/0090-1229(83)90084-3
发表时间:
1983
期刊:
Clinical immunology and immunopathology
影响因子:
--
作者:
Ammann,AJ;Abrams,D;Conant,M;Chudwin,D;Cowan,M;Volberding,P;Lewis,B;Casavant,C
通讯作者:
Casavant,C
DOI:
10.1016/0090-1229(83)90083-1
发表时间:
1983
期刊:
Clinical immunology and immunopathology
影响因子:
--
作者:
Schroff,RW;Gottlieb,MS;Prince,HE;Chai,LL;Fahey,JL
通讯作者:
Fahey,JL