Bottom-Up Assembled Photonic Crystals for Structure-Enabled Label-Free Sensing.

Bottom-Up Assembled Photonic Crystals for Structure-Enabled Label-Free Sensing.
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DOI:
10.1021/acsnano.1c02495
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发表时间:
2021-06-22
期刊:
影响因子:
17.1
通讯作者:
Eijkel JCT
Eijkel JCT
中科院分区:
材料科学1区
文献类型:
--
作者:
Wang J;Pinkse PWH;Segerink LI;Eijkel JCT

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光子晶体 (PhC) 显示光子阻带 (PSB),并且在这些 PSB 的边缘以降低的速度传输光,使 PhC 能够通过增强的光与物质相互作用来限制和操纵入射光。人们一直致力于利用光子晶体的光学特性来开发用于生物测定、诊断和环境监测的光学传感器。这些应用还受益于 PhC 固有的大表面积,从而产生高分析物吸附性和 PhC 结构变化的广泛选择,从而增强光与物质的相互作用。在这里,我们重点关注自下而上组装的光子晶体,并回顾它们在用作无标记传感器方面所取得的重大进展。我们描述了它们在护理点设备方面的潜力,并在审查中包括它们的结构设计、组成材料、制造策略和传感工作原理。因此,我们根据五种传感原理对它们进行分类:折射率变化的传感、晶格间距变化的传感、增强荧光光谱、表面增强拉曼光谱和构型跃迁。
Photonic crystals (PhCs) display photonic stop bands (PSBs) and at the edges of these PSBs transport light with reduced velocity, enabling the PhCs to confine and manipulate incident light with enhanced light–matter interaction. Intense research has been devoted to leveraging the optical properties of PhCs for the development of optical sensors for bioassays, diagnosis, and environmental monitoring. These applications have furthermore benefited from the inherently large surface area of PhCs, giving rise to high analyte adsorption and the wide range of options for structural variations of the PhCs leading to enhanced light–matter interaction. Here, we focus on bottom-up assembled PhCs and review the significant advances that have been made in their use as label-free sensors. We describe their potential for point-of-care devices and in the review include their structural design, constituent materials, fabrication strategy, and sensing working principles. We thereby classify them according to five sensing principles: sensing of refractive index variations, sensing by lattice spacing variations, enhanced fluorescence spectroscopy, surface-enhanced Raman spectroscopy, and configuration transitions.
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