Are Grid-Like Representations a Component of All Perception and Cognition?

Are Grid-Like Representations a Component of All Perception and Cognition?
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DOI:
10.3389/fncir.2022.924016
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发表时间:
2022
影响因子:
3.5
通讯作者:
--
中科院分区:
医学3区
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--
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据报道,在啮齿类动物、蝙蝠和人脑中,在各种空间和非空间任务中都存在网格细胞或网格样反应。然而,经典的海马区结构之外的网格状表征的功能仍然难以捉摸。基于最近的啮齿动物记录和人类功能磁共振数据积累的证据,我们对感觉皮质网状细胞的机制和功能意义进行了推测,并进一步做出了理论驱动的预测。我们论证并推理了为什么网格反应在大脑中对于涉及运动和精神导航的广泛的知觉和认知任务是普遍的。计算建模可以提供一种替代的和补充的手段来研究网格代码或类似网格的地图。我们希望新的讨论将导致实验上可验证的假说,并推动未来的实验数据收集。
Grid cells or grid-like responses have been reported in the rodent, bat and human brains during various spatial and non-spatial tasks. However, the functions of grid-like representations beyond the classical hippocampal formation remain elusive. Based on accumulating evidence from recent rodent recordings and human fMRI data, we make speculative accounts regarding the mechanisms and functional significance of the sensory cortical grid cells and further make theory-driven predictions. We argue and reason the rationale why grid responses may be universal in the brain for a wide range of perceptual and cognitive tasks that involve locomotion and mental navigation. Computational modeling may provide an alternative and complementary means to investigate the grid code or grid-like map. We hope that the new discussion will lead to experimentally testable hypotheses and drive future experimental data collection.
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