Weight trajectories and obesity remission among school-aged children.

Weight trajectories and obesity remission among school-aged children.
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DOI:
10.1371/journal.pone.0290565
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发表时间:
2023
期刊:
影响因子:
3.7
通讯作者:
--
中科院分区:
综合性期刊3区
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--
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许多检查体重轨迹的研究都使用了肥胖测量方法,这被证明对肥胖儿童的轨迹分析是有问题的,而且肥胖症的缓解仍然知之甚少。描述学龄儿童的体重轨迹、肥胖缓解率和相关因素。俄勒冈州一家医院系统在至少6个月内对6至11岁的儿童进行了≥3有效身高和体重测量。模型采用与体重指数(BMI)中位数的百分比距离。采用潜在类分析和线性混合模型对儿童的体重轨迹进行分类。我们纳入了11,247名受试者,平均随访时间为2.1年,其中1,614人(14.4%)被归类为超重,1,794人(16.0%)被归类为肥胖。在肥胖者中,1%的人在随访期间经历了缓解,而23%的超重者转移到了健康的体重范围内。随着时间的推移,潜在类别分析在每个基于权重的地层中确定了三个类别。大多数超重或肥胖的儿童随着时间的推移有一个平坦的轨迹。较低的社会经济地位与不断恶化的轨迹有关。使用其他测量方法(BMI、BMI z-Score、三重质量指数(TMI))的潜在类别模型彼此之间有很大的不同。虽然从超重到健康体重的转变更常见,但使用距离中位数的肥胖度衡量标准,肥胖缓解并不常见。社会经济地位较低的儿童总体上的发展轨迹更差。肥胖指标的选择可能对结果有很大的影响。
Many studies examining weight trajectories have used adiposity measures shown to be problematic for trajectory analysis in children with obesity, and remission of obesity remains poorly understood. To describe weight trajectories for school-aged children, the rate of obesity remission and factors associated. Children between 6 and 11 years of age with ≥3 valid height and weight measurements from an Oregon hospital-system over a minimum six-month period were included. Percent distance from the median body mass index (BMI) was used for modeling. Latent class analysis and linear mixed models were used to classify children based on their weight trajectory. We included 11,247 subjects with a median of 2.1 years of follow-up, with 1,614 (14.4%) classified as overweight and 1,794 (16.0%) classified as obese. Of subjects with obesity, 1% experienced remission during follow-up, whereas 23% of those with overweight moved to within a healthy weight range. Latent class analysis identified three classes within each weight-based stratum over time. The majority of children with overweight or obesity had a flat trajectory over time. Lower socioeconomic status was associated with a worsening trajectory. Latent class models using alternate measures (BMI, BMI z-scores, tri-ponderal mass index (TMI)) differed substantially from each other. Obesity remission was uncommon using the adiposity metric of distance from the median though transition from overweight to healthy weight was more common. Children with low socioeconomic status have worse trajectories overall. The choice of adiposity metric may have a substantial effect on the outcomes.
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