The HTLV-1 Tax interactome.

The HTLV-1 Tax interactome.
复制标题

DOI:
10.1186/1742-4690-5-76
复制
发表时间:
2008-08-14
期刊:
影响因子:
3.3
通讯作者:
Willems L
Willems L
中科院分区:
医学2区
文献类型:
--
作者:
Boxus M;Twizere JC;Legros S;Dewulf JF;Kettmann R;Willems L

文献摘要

参考文献

被引文献

相似文献

由人类嗜T淋巴细胞病毒I型编码的Tax1癌蛋白是病毒持续存在和致病的主要决定因素。Tax1影响多种细胞信号传导途径,导致转录激活、增殖和最终转化。为了实现这些功能,Tax1与许多细胞蛋白相互作用并调节其活性。在这篇综述中,我们总结了Tax1相互作用组的现有知识,并提出了一个理由,迄今为止,广泛的细胞蛋白质。
The Tax1 oncoprotein encoded by Human T-lymphotropic virus type I is a major determinant of viral persistence and pathogenesis. Tax1 affects a wide variety of cellular signalling pathways leading to transcriptional activation, proliferation and ultimately transformation. To carry out these functions, Tax1 interacts with and modulates activity of a number of cellular proteins. In this review, we summarize the present knowledge of the Tax1 interactome and propose a rationale for the broad range of cellular proteins identified so far.
DOI: 10.1093/nar/gkj052
发表时间: 2006-01-01
影响因子: 14.9
作者:
Bakheet T;Williams BR;Khabar KS
通讯作者: Khabar KS
DOI: 10.1182/blood-2001-12-0372
发表时间: 2002-12-01
期刊: BLOOD
影响因子: 20.3
作者:
Arnulf, B;Villemain, A;Hermine, O
通讯作者: Hermine, O
DOI: 10.1128/mcb.18.4.2392
发表时间: 1998-04-01
影响因子: 5.3
作者:
Bex, F;Yin, MJ;Gaynor, RB
通讯作者: Gaynor, RB
DOI: 10.1128/mcb.14.2.1374
发表时间: 1994-02-01
影响因子: 5.3
作者:
BERAUD, C;SUN, SC;GREENE, WC
通讯作者: GREENE, WC
DOI: 10.1073/pnas.0608832104
发表时间: 2007-05-08
影响因子: 11.1
作者:
Asquith, Becca;Zhang, Yan;Bangham, Charles R. M.
通讯作者: Bangham, Charles R. M.