Subversion of the cytoskeleton by intracellular bacteria: lessons from Listeria, Salmonella and Vibrio.
Subversion of the cytoskeleton by intracellular bacteria: lessons from Listeria, Salmonella and Vibrio.
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DOI:
10.1111/cmi.12399
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发表时间:
2015-03
影响因子:
3.4
通讯作者:
Orth K
中科院分区:
文献类型:
--
作者:
de Souza Santos M;Orth K
Entry into host cells and intracellular persistence by invasive bacteria are tightly coupled to the ability of the bacterium to disrupt the eukaryotic cytoskeletal machinery. Herein we review the main strategies used by three intracellular pathogens to harness key modulators of the cytoskeleton. Two of these bacteria, namely Listeria monocytogenes and Salmonella enterica serovar Typhimurium, exhibit quite distinct intracellular lifestyles, and therefore, provide a comprehensive panel for the understanding of the intricate bacteria-cytoskeleton interplay during infections. The emerging intracellular pathogen Vibrio parahaemolyticus is depicted as a developing model for the uncovering of novel mechanisms used to hijack the cytoskeleton.
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