Sodium‐dependent accumulation of 5‐hydroxytryptamine by rat blood platelets

Sodium‐dependent accumulation of 5‐hydroxytryptamine by rat blood platelets
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大鼠血小板钠依赖性积累 5-羟色胺

DOI:
10.1111/j.1476-5381.1969.tb08506.x
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发表时间:
1969
影响因子:
7.3
通讯作者:
J. Sneddon
J. Sneddon
中科院分区:
医学2区
文献类型:
--
作者:
J. Sneddon

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1 .研究了钠和钾对大鼠血小板蓄积5-羟色胺(5-HT)的影响。二、5-HT摄取量与培养液中钠浓度呈绝对依赖关系。去除钾使吸收减少约60%高浓度的钾抑制钠依赖性蓄积。四、观察结果已经讨论了在血小板膜中操作的5-HT的载体介导的转运过程。
1 . The influence of sodium and potassium on the accumulation of 5‐hydroxytryptamine (5‐HT) by rat blood platelets was investigated. 2 . An absolute dependence of 5‐HT uptake on the sodium concentration in the medium was found. 3 . Removal of potassium reduced the uptake by about 60% High concentrations of potassium inhibited sodium‐dependent accumulation. 4 . The observations have been discussed in terms of a carrier‐mediated transport process for 5‐HT operating in the platelet membrane.
影响人体血小板吸收血清素的因素。
DOI: 10.1007/bf00174506
发表时间: 1988
期刊: Psychopharmacology
影响因子: 3.4
作者:
Codd,EE;McAllister,TW;Walker,RF
通讯作者: Walker,RF