Crystal structure of a group II intron in the pre-catalytic state.
Crystal structure of a group II intron in the pre-catalytic state.
复制标题
DOI:
10.1038/nsmb.2270
复制
发表时间:
2012-04-08
影响因子:
16.8
通讯作者:
Toor, Navtej
中科院分区:
文献类型:
--
作者:
Chan, Russell T.;Robart, Aaron R.;Rajashankar, Kanagalaghatta R.;Pyle, Anna Marie;Toor, Navtej
Group II introns are self-splicing catalytic RNAs that are thought to be ancestral to the spliceosome. Here we report the 3.65 Å crystal structure of the group II intron from Oceanobacillus iheyensis in the pre-catalytic state. The structure reveals the conformation of the 5′ splice site in the catalytic core and represents the first structure of an intron prior to the first step of splicing.
登录
查看更多内容
影响因子:
16
作者:
Dai, Lixin;Chai, Dinggeng;Zimmerly, Steven
通讯作者:
Zimmerly, Steven
影响因子:
4.5
作者:
Robart, AR;Montgomery, NK;Zimmerly, S
通讯作者:
Zimmerly, S
影响因子:
64.8
作者:
Boudvillain, M;de Lencastre, A;Pyle, AM
通讯作者:
Pyle, AM
影响因子:
16.8
作者:
通讯作者:
--
影响因子:
5.6
作者:
JACQUIER, A;MICHEL, F
通讯作者:
MICHEL, F