Inhibitory Control of Lexical Selection in Adults who Stutter.

Inhibitory Control of Lexical Selection in Adults who Stutter.
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DOI:
10.1016/j.jfludis.2020.105780
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发表时间:
2020-12
影响因子:
2.1
通讯作者:
Maxfield ND
Maxfield ND
中科院分区:
医学2区
文献类型:
--
作者:
Maxfield ND

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基于先前的证据表明,词汇选择可能在口吃的成年人(AWS)与典型流利的成年人(TFA)不同的运作,以及非典型注意加工可能是一个贡献因素,本研究的目的是调查抑制控制的词汇选择在AWS。12架AWS和12架TFA完成了两项任务。一个是图片命名任务,具有高和低协议对象命名。记录动作准确性和反应时间(RT),以及事件相关电位(ERP)时间锁定到图片开始。第二个是侧翼任务,具有一致和不一致的箭头阵列。记录按钮准确性和RT,以及时间锁定到箭头阵列开始的ERP。在两组中,低一致性图片的命名准确度和速度均低于高一致性图片。在AWS中,命名RT的一致性效应的幅度大于TFA。三角形图分析表明,协议效果与个体差异抑制TFA,但不AWS呈正相关。此外,低协议图片引起了负向ERP活动相对于高协议的图片在两组。然而,这种效果的头皮地形显着减少AWS与TFA。对于Flanker任务,一致性对按钮准确性、RT和N2振幅的影响在组间也类似。结果表明,在AWS的词汇选择抑制控制的选择性赤字。词汇选择抑制控制减弱、言语运动控制减弱和口吃之间的可能通路也被讨论。
Based on previous evidence that lexical selection may operate differently in adults who stutter (AWS) versus typically-fluent adults (TFA), and that atypical attentional processing may be a contributing factor, the purpose of this study was to investigate inhibitory control of lexical selection in AWS. 12 AWS and 12 TFA completed two tasks. One was a picture naming task featuring High and Low Agreement object naming. Naming accuracy and reaction times (RT), and event-related potentials (ERPs) time-locked to picture onset, were recorded. Second was a flanker task featuring Congruent and Incongruent arrow arrays. Push-button accuracy and RTs, and ERPs time-locked to arrow array onset, were recorded. Low Agreement pictures were named less accurately and slower than High Agreement pictures in both Groups. The magnitude of the Agreement effect on naming RTs was larger in AWS versus TFA. Delta-plot analysis revealed that the Agreement effect was positively correlated with individual differences in inhibition in TFA but not in AWS. Moreover, Low Agreement pictures elicited negative-going ERP activity relative to High Agreement pictures in both Groups. However, the scalp topography of this effect was markedly reduced in AWS versus TFA. For the Flanker task, Congruency affected push-button accuracy and RTs, and N2 amplitudes, similarly between groups. Results point to a selective deficit in inhibitory control of lexical selection in AWS. Potential pathways between diminished inhibitory control of lexical selection, speech motor control and stuttering are discussed.
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