Reductions in Cardiac Structure and Function 24 Months After Spinal Cord Injury: A Cross-Sectional Study.
Reductions in Cardiac Structure and Function 24 Months After Spinal Cord Injury: A Cross-Sectional Study.
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DOI：
10.1016/j.apmr.2021.01.070
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发表时间：
2021-08
影响因子：
4.3
通讯作者：
Taylor JA
中科院分区：
文献类型：
--
作者：
Ely MR;Singh TK;Baggish AL;Taylor JA
确定脊髓损伤后数月内心脏结构和功能的变化。脊髓损伤后3至24个月的29名（4F）志愿者。对每名志愿者进行经胸超声心动图检查。通过多元线性回归评估损伤后时间、神经和感觉损伤水平与心脏结构/功能的关系。损伤后的时间与左心室舒张末期容积（r2 = 0.156，p = 0.034）、收缩末期容积（r2 = 0.141，p = 0.045）和质量（r2 = 0.138，p = 0.047）的减少密切相关。这些结构变化被减少的每搏输出量（r2 = 0.143 p = 0.043）和心输出量（r2 = 0.317，p = 0.002，<0.001）所抵消。左心室结构和收缩功能的降低不受神经或感觉损伤水平的影响（p = 0.084-0.921）。这些结果表明SCI后3 - 24个月左心室结构和收缩功能的逐渐降低与神经和感觉损伤水平无关。
To determine the alterations in cardiac structure and function that occur in the months following spinal cord injury. Cross-sectional Rehabilitation Hospital Twenty-nine (4F) volunteers 3 to 24 months post spinal cord injury. Transthoracic echocardiography was performed on each volunteer. The relationships of time since injury and neurological and sensory levels of injury to cardiac structure/function was assessed via multiple linear regression. Time since injury was most strongly associated with reductions in left ventricular end-diastolic volume (r2 = 0.156, p = 0.034), end-systolic volume (r2 = 0.141, p = 0.045), and mass (r2 = 0.138, p = 0.047). These structural changes were paralleled by reduced stroke volume (r2 = 0.143 p = 0.043) and cardiac output (r2 = 0.317, p = 0.002, <0.001). The reductions in left ventricular structure and systolic function were not differentially affected by neurological or sensory levels of injury (p = 0.084–0.921). These results suggest progressive reductions in left ventricular structure and systolic function from 3 to 24 months following SCI that occur independent of neurological and sensory levels of injury.
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DOI：
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发表时间：
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期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
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发表时间：
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影响因子：
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DOI：
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发表时间：
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影响因子：
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