Acidification and sodium entry in frog skin epithelium.
Acidification and sodium entry in frog skin epithelium.
复制标题
青蛙皮肤上皮的酸化和钠进入。
DOI:
10.1016/0005-2736(81)90293-5
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发表时间:
1981
期刊:
影响因子:
--
通讯作者:
Benos,DJ
中科院分区:
文献类型:
--
作者:
Benos,DJ
Acidification of the external medium by isolated frog skin epithelium (Rana catesbeiana, Rana temporaria, andCaudiververa caudiververa) and its relationship to Na+uptake was studied. Acidification was measured by the pH-stat technique under short-circuit or open-circuit conditions. The results of this study demonstrate that (a) acidification by these species of in vitro frog skins is not directly coupled to Na+or anion transport; (b) acidification can be inhibited by the diuretic drug amiloride, but only at high external Na+concentrations; (c) acidification rate in these species of frog skin is controlled in part by the metabolic production of CO2; and (d) the positive correlation between net Na+absorption and net acidification observed in whole animal studies could not be replicated in the in vitro skin preparation, even when the frogs were first chronically stressed by salt depletion, a physiological state comparable to that used in the in vivo experiments.
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影响因子:
64.8
作者:
J. D. Johnson;D. Epel;M. Paul
通讯作者:
M. Paul
DOI:
--
发表时间:
1977
期刊:
The Journal of General Physiology
影响因子:
--
作者:
R. Fisher
通讯作者:
R. Fisher
DOI:
--
发表时间:
1977
期刊:
Journal of Physiology
影响因子:
--
作者:
R. Thomas
通讯作者:
R. Thomas
影响因子:
--
作者:
R. T. Whitlock;H. O. Wheeler
通讯作者:
H. O. Wheeler
DOI:
--
发表时间:
1975
期刊:
Biochimica et Biophysica Acta
影响因子:
--
作者:
T. Machen;D. Erlij
通讯作者:
D. Erlij