Primary COVID-19 vaccine cycle and booster doses efficacy: analysis of Italian nationwide vaccination campaign.

Primary COVID-19 vaccine cycle and booster doses efficacy: analysis of Italian nationwide vaccination campaign.
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DOI:
10.1093/eurpub/ckab220
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发表时间:
2022-04-01
影响因子:
4.4
通讯作者:
Lippi G
Lippi G
中科院分区:
医学3区
文献类型:
--
作者:
Mattiuzzi C;Lippi G

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我们在此提供意大利正在进行的全国新冠肺炎疫苗接种活动中出现的初级新冠肺炎疫苗接种和疫苗强化剂量效力的最新分析。初次接种新冠肺炎的有效率在6个 月内为76~92%,6个 月后降至34~80%。在6个 月内,与疫苗效果相比,加强剂量组的SARS-CoV-2感染下降了65%,与新冠肺炎相关的住院率和死亡率分别下降了69%和97%,但同时也使SARS-CoV-2感染下降了39%。这些结果表明,新冠肺炎疫苗加强剂量对于恢复疫苗效力和进一步限制病毒传播非常重要。
We provide here an updated analysis of primary COVID-19 vaccination and vaccine booster doses efficacy, emerging from the ongoing Italian nationwide COVID-19 vaccination campaign. Primary COVID-19 vaccination efficacy was 76–92% within 6 months, decreasing to 34–80% after 6 months. Administration of vaccine booster doses decreased SARS-CoV-2 infections by 65%, COVID-19-related hospitalizations and deaths by 69% and 97% compared with vaccine efficacy after 6 months, but also decreased SARS-CoV-2 infections by 39% compared with vaccine efficacy within 6 months. These results suggest that COVID-19 vaccine booster doses are important for restoring vaccine efficacy and further limiting virus circulation.
DOI: 10.1056/nejmoa2114255
发表时间: 2021-10-07
期刊: The New England journal of medicine
影响因子: --
作者:
Bar-On YM;Goldberg Y;Mandel M;Bodenheimer O;Freedman L;Kalkstein N;Mizrahi B;Alroy-Preis S;Ash N;Milo R;Huppert A
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DOI: 10.1093/eurpub/ckab144
发表时间: 2021-10-26
影响因子: 4.4
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Meijer M;Verschuuren M;Weggen E
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DOI: 10.1038/s41579-021-00573-0
发表时间: 2021-07
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影响因子: --
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Harvey WT;Carabelli AM;Jackson B;Gupta RK;Thomson EC;Harrison EM;Ludden C;Reeve R;Rambaut A;COVID-19 Genomics UK (COG-UK) Consortium;Peacock SJ;Robertson DL
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期刊: The New England journal of medicine
影响因子: --
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Goldberg Y;Mandel M;Bar-On YM;Bodenheimer O;Freedman L;Haas EJ;Milo R;Alroy-Preis S;Ash N;Huppert A
通讯作者: Huppert A