Identifying and Measuring Endogenous Peptides through Peptidomics.

Identifying and Measuring Endogenous Peptides through Peptidomics.
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通过肽组学识别和测量内源肽。

DOI:
10.1021/acschemneuro.3c00546
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发表时间:
2023
影响因子:
5
通讯作者:
Checco,JamesW
Checco,JamesW
中科院分区:
医学3区
文献类型:
--
作者:
Checco,JamesW

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内源性肽,如神经肽和肽激素,在细胞间通讯中起着重要作用,可以提供生理信息,是生物标志物的潜在来源。质谱为基础的肽组学方法是未充分利用的工具,以相对非靶向的方式识别和测量内源性肽。本观点的目的是作为肽组学领域的简要介绍,以便对内源性肽研究感兴趣的研究人员了解这种强大的方法并可以考虑其应用。
Endogenous peptides, such as neuropeptides and peptide hormones, play important roles in intercellular communication, can provide information on physiology, and are potential sources of biomarkers. Mass spectrometry-based peptidomics methods are underutilized tools to identify and measure endogenous peptides in a relatively nontargeted manner. The purpose of this Viewpoint is to serve as a brief introduction to the field of peptidomics so that researchers interested in studying endogenous peptides are aware of this powerful approach and can consider its application.
DOI: 10.1021/acschemneuro.2c00359
发表时间: 2022-10-05
影响因子: 5
作者:
Mousavi S;Qiu H;Heinis FI;Abid MSR;Andrews MT;Checco JW
通讯作者: Checco JW
DOI: 10.1021/acschemneuro.3c00268
发表时间: 2023-07-03
影响因子: 5
作者:
Mousavi,Somayeh;Qiu,Haowen;Checco,James W.
通讯作者: Checco,James W.