Neural mechanisms of concurrent stimulus processing in dual tasks
Neural mechanisms of concurrent stimulus processing in dual tasks
复制标题
双任务中并发刺激处理的神经机制
DOI：
10.1016/j.neuroimage.2009.06.064
复制
发表时间：
2009
期刊：
影响因子：
5.7
通讯作者：
T. Schubert
中科院分区：
文献类型：
--
作者：
C. Stelzel;S. Brandt;T. Schubert
关于人类大脑如何处理竞争行为的多个相关信息流，我们所知甚少。本研究旨在研究在经典双任务情境下，侧前额叶皮层（lPFC）与任务相关感觉脑区在同时处理两个相关刺激（S1、S2）时的相互作用。具体而言，我们测试了S1加工是否独立于S2的任务相关性，正如双任务加工的认知理论所假设的那样。利用功能性磁共振成像技术，我们测试了两种可能反映不同时间重叠时S2关联对S1加工影响的神经机制。结果表明：(1)当S2相关或不相关时，下颞叶皮层s1相关区域的活动振幅同样受到两种刺激时间重叠的影响；(2)只有当S2在双任务中相关时，高时间重叠时，后lPFC s1相关区域与双任务相关区域之间的功能耦合才会显著增加。在s2相关区域没有发现类似的效应。这些发现表明，双重任务中的并发刺激处理是通过相对高优先级刺激的功能耦合的短暂变化来实现的（S1）。
Little is known about how the human brain processes multiple relevant information streams competing for behavior. The present study aimed at specifying the interaction of the lateral prefrontal cortex (lPFC) with task-relevant sensory brain regions during concurrent stimulus processing of two relevant stimuli (S1, S2) in a classical dual-task situation. In detail, we tested whether S1 processing is independent of the task relevance of S2 as has been hypothesised in cognitive theories on dual-task processing. Using functional Magnetic Resonance Imaging, we tested two neural mechanisms that might reflect effects of S2 relevance on S1 processing at different temporal overlaps. The results indicate that: (1) activity amplitudes in S1-relevant regions in the inferior temporal cortex were similarly affected by the temporal overlap between the two stimuli when S2 was relevant or irrelevant and (2) only when S2 was relevant in the dual task, significant increases in the functional coupling between S1-relevant regions and dual-task-related regions in the posterior lPFC were present at high temporal overlap. No similar effects were found for S2-relevant regions. These findings suggest that concurrent stimulus processing in dual tasks is realised by transient changes in functional coupling for stimuli with relatively higher priority (S1).
DOI：
10.1073/pnas.95.3.914
发表时间：
1998-02-03
影响因子：
11.1
作者：
Fiez, JA;Petersen, SE
通讯作者：
Petersen, SE