Evaluation of electric field distribution in electromagnetic stimulation of human femoral head

Evaluation of electric field distribution in electromagnetic stimulation of human femoral head
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人体股骨头电磁刺激电场分布评价

DOI:
10.1002/bem.21879
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发表时间:
2014
影响因子:
1.9
通讯作者:
Bader R
Bader R
中科院分区:
生物学4区
文献类型:
--
作者:
Souffrant R;Kluess D;Ellenrieder M;Mittelmeier W;van Rienen U;Bader R

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在股骨头缺血性坏死的情况下,电磁刺激是用于支持骨愈合的常用疗法。在本研究中,我们研究了一个双极感应螺旋系统与集成线圈。目的是分析螺钉参数对人体股骨头内电场分布的影响。此外,三种设计参数(螺钉头端形状、螺钉在股骨头中的位置和螺钉绝缘层尺寸)不同。使用有限元软件Comsol Multiphysics计算骨中的电场分布。此外,对植入螺钉的相同骨标本进行了验证实验。测量了骨内和骨表面点的电位,并与数值数据进行了比较。不同的植入参数明显改变了骨内的电场分布。重新定位螺钉最多10 mm,改变绝缘长度最多4 mm,分别导致电场体积变化16%和7%。通过将数值模拟的结果与验证实验的数据进行比较,平均而言,当测量点位于股骨内约5 mm的深度处和直接位于股骨表面上时,分别发生19%和24%的电位差。数值模拟的结果强调,临床应用中骨的电刺激治疗可能会受到植入物参数的影响。Bioelectromagnetics 35:547-558,2014.© 2014 Wiley Periodicals,Inc.
Electromagnetic stimulation is a common therapy used to support bone healing in the case of avascular necrosis of the femoral head. In the present study, we investigated a bipolar induction screw system with an integrated coil. The aim was to analyse the influence of the screw parameters on the electric field distribution in the human femoral head. In addition, three kinds of design parameters (the shape of the screw tip, position of the screw in the femoral head, and size of the screw insulation) were varied. The electric field distribution in the bone was calculated using the finite element software Comsol Multiphysics. Moreover, a validation experiment was set up for an identical bone specimen with an implanted screw. The electric potential of points inside and on the surface of the bone were measured and compared to numerical data. The electric field distribution within the bone was clearly changed by the different implant parameters. Repositioning the screw by a maximum of 10 mm and changing the insulation length by a maximum of 4 mm resulted in electric field volume changes of 16% and 7%, respectively. By comparing the results of numerical simulation with the data of the validation experiment, on average, the electric potential difference of 19% and 24% occurred when the measuring points were at a depth of approximately 5 mm within the femoral bone and directly on the surface of the femoral bone, respectively. The results of the numerical simulations underline that the electro‐stimulation treatment of bone in clinical applications can be influenced by the implant parameters. Bioelectromagnetics 35:547–558, 2014. © 2014 Wiley Periodicals, Inc.
DOI: 10.4103/0019-5413.50846
发表时间: 2009-04
影响因子: 1
作者:
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通讯作者: Schemitsch EH
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发表时间: 2013
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发表时间: 1999-07-01
期刊: SPINE
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发表时间: 1981-01-01
影响因子: 5.3
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DOI: 10.1007/bf02667351
发表时间: 1996
影响因子: 3.8
作者:
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