Display modes for CT colonography. Part I. Synthesis and insertion of polyps into patient CT data.

Display modes for CT colonography. Part I. Synthesis and insertion of polyps into patient CT data.
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CT 结肠成像的显示模式。

DOI:
10.1148/radiology.212.1.r99jl25195
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发表时间:
1999
期刊:
影响因子:
19.7
通讯作者:
Napel,S
Napel,S
中科院分区:
医学1区
文献类型:
--
作者:
Karadi,C;Beaulieu,CF;JeffreyJr,RB;Paik,DS;Napel,S

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目的:开发和验证一种将数字合成的息肉插入到人体结肠的CT图像中作为评估虚拟结肠镜检查的基础的方法。材料和方法:使用螺旋CT模拟器软件生成10个不同结构的合成息肉。开发了额外的软件,将这些息肉插入到体积CT扫描中。选择8例患者的10个息肉进行比较。三位放射科医生评估了二维(2D)CT图像和三维(3D)体积再现CT图像是否显示合成息肉或真实息肉。结果:模拟息肉的边缘响应曲线和噪声与自然息肉一致。在3D或2D图像中,对于合成息肉和真实息肉,评价者反应的频率分布没有显著差异。反应集中在“不确定”的反应周围是真的还是合成的损伤。3D图像和2D图像的受试者工作特征曲线的面积分别为0.54(95%CI=0.39,0.68)和0.39(95%CI=0.25,0.53),与随机猜测的结果(3D图像和2D图像分别为0.70和0.28)相比,差异无统计学意义。该方法可用于生成地面真实实验数据,用于比较CT结肠成像显示和检测方法。
PURPOSE:To develop and validate a method for the insertion of digitally synthesized polyps into computed tomographic (CT) images of the human colon for use as ground truth for evaluation of virtual colonoscopy.MATERIALS AND METHODS:Spiral CT simulator software was used to generate 10 synthetic polyps in various configurations. Additional software was developed to insert these polyps into volume CT scans. Ten polyps in eight patients were selected for comparison. Three radiologists evaluated whether two-dimensional (2D) CT images and three-dimensional (3D) volume-rendered CT images showed synthetic or real polyps.RESULTS:Edge-response profiles and noise of simulated polyps matched those of native polyps. Frequency distributions of reviewers' responses were not significantly different for synthetic versus real polyps in either 3D or 2D images. Responses were clustered around the response of “unsure” if lesions were real or synthetic. Receiver operating characteristic curves had areas of 0.54 (95% CI = 0.39, 0.68) for 3D and 0.39 (95% CI = 0.25, 0.53) for 2D images, which were not significantly different from random guessing (P= .70 and .28 for 3D and 2D images, respectively).CONCLUSION:Synthetic polyps were indistinguishable from real polyps. This method can be used to generate ground truth experimental data for comparison of CT colonographic display and detection methods.
DOI: 10.1148/radiology.205.3.9393527
发表时间: 1997-12
期刊: Radiology
影响因子: 19.7
作者:
T. Vogl;A. Stupavsky;W. Pegios;R. Hammerstingl;M. Mack;T. Diebold;K. Lodemann;P. Neuhaus;R. Felix
通讯作者: T. Vogl;A. Stupavsky;W. Pegios;R. Hammerstingl;M. Mack;T. Diebold;K. Lodemann;P. Neuhaus;R. Felix
使用 CT 结肠成像检测结直肠息肉:二维技术与三维技术。
DOI: 10.1148/radiology.200.1.8657944
发表时间: 1996
期刊: Radiology
影响因子: 19.7
作者:
Ayako Hara;C. Johnson;J. Reed;R. Ehman;D. Ilstrup
通讯作者: D. Ilstrup
DOI: 10.1148/radiology.212.1.r99jl17203
发表时间: 1999
期刊: Radiology
影响因子: 19.7
作者:
Beaulieu,CF;JeffreyJr,RB;Karadi,C;Paik,DS;Napel,S
通讯作者: Napel,S
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DOI: 10.1148/radiology.199.2.8668772
发表时间: 1996
期刊: Radiology.
影响因子: --
作者:
Rubin,GD;Beaulieu,CF;Argiro,V;Ringl,H;Norbash,AM;Feller,JF;Dake,MD;Jeffrey,RB;Napel,S
通讯作者: Napel,S
DOI: 10.1118/1.598244
发表时间: 1998-05-01
期刊: MEDICAL PHYSICS
影响因子: 3.8
作者:
Paik, DS;Beaulieu, CF;Napel, S
通讯作者: Napel, S