Alternating field electrospinning of blended fish gelatin/poly(ε-caprolactone) nanofibers
Alternating field electrospinning of blended fish gelatin/poly(ε-caprolactone) nanofibers
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鱼明胶/聚己内酯混合纳米纤维的交变电场静电纺丝
DOI：
10.1016/j.matlet.2023.134284
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发表时间：
2023
影响因子：
3
通讯作者：
Stanishevsky, Andrei
中科院分区：
文献类型：
--
作者：
Lacy, Hannah A.;Jenčová, Věra;Lukáš, David;Stanishevsky, Andrei
来自天然和合成来源的混合纳米纤维生物材料显示出更好的生物整合前景。本研究探索了混合冷水鱼皮明胶(FGEL)和聚己内酯(PCL)纳米纤维网的高效交流电场纺丝(AFES)，其PCL含量高达30wt%，纤维生产率为7.8-14.4微克/小时，具体取决于组成。热交联后的FGEL/PCL纳米纤维表面光滑，平均直径237~313 nm。FTIR分析表明，FGEL/PCL相互作用很小，PCL结晶度发生了显著变化。14天的体外分析显示良好的细胞活性和纳米纤维FGEL/PCL网状物的稳定性。结果表明，AFES提供了高效、可扩展的FGEL/PCL纳米纤维生物材料的生产，且具有合适的特性。
Blended nanofibrous biomaterials from natural and synthetic sources show promise for better biointegration. This study explores high-yield alternating field electrospinning (AFES) of blended cold-water fish skin gelatin (FGEL) and polycaprolactone (PCL) nanofibrous meshes with up to 30 wt% PCL at 7.8–14.4 g/h fiber productivity, depending on the composition. FGEL/PCL nanofibers reveal smooth surface morphology and 237–313 nm average diameters after thermal crosslinking. FTIR analysis indicated little FGEL/PCL interaction and notable changes in PCL crystallinity in the crosslinked nanofibers. A 14-daysin-vitroanalysis shows good cellular viability and nanofibrous FGEL/PCL mesh stability. Results demonstrate that AFES provides efficient, scalable production of blended FGEL/PCL nanofibrous biomaterials with suitable characteristics.
影响因子：
3.8
作者：
Amanda Kennell;Mark W Macewen;M. Armstrong;T. Nicola;B. Halloran;N. Ambalavanan;A. Stanishevsky
通讯作者：
Amanda Kennell;Mark W Macewen;M. Armstrong;T. Nicola;B. Halloran;N. Ambalavanan;A. Stanishevsky
鱼明胶：当前的营养、药用、组织修复应用和药物输送载体。
影响因子：
3.1
作者：
Amro M. Soliman;S. Teoh;Srijit Das
通讯作者：
Srijit Das