Imaging cognitive reserve

Imaging cognitive reserve
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影像认知储备

DOI:
10.1080/00207590344000259
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发表时间:
2004
影响因子:
3.2
通讯作者:
C. Habeck
C. Habeck
中科院分区:
心理学4区
文献类型:
--
作者:
Y. Stern;N. Scarmeas;C. Habeck

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我们回顾了三项试图探索认知储备(CR)的神经基础的研究。所有的研究都利用了视觉识别任务的两种条件:低要求条件和另一种难度滴定的条件,使所有受试者的识别准确率达到75%。我们假设任务相关的激活模式不同,作为CR的代理测量函数。前两项研究集中在年轻受试者身上,发现从低需求到滴定需求的激活量增加与CR相关的大脑区域或大脑网络。第三项研究比较了年轻人和老年人的激活模式。与之前的研究一样,在两组大脑中发现,作为CR的功能,激活的区域是不同的。最值得注意的是,在两组中,激活和CR之间的关系是不同的。这些发现为认知储备的初步神经实现提供了基础。他们还建议……
We review three studies that attempt to explore the neural substrates of cognitive reserve (CR). All studies utilize two conditions of a visual recognition task: a low demand condition, and another where difficulty was titrated such that all subjects performed at 75% recognition accuracy. We hypothesized that there would be different patterns of task‐related activation as a function of a proxy measure of CR. The first two studies focused on young subjects, and found either brain areas or brain networks where the amount of increased activation from low to titrated demand correlated with CR. The third study compared activation patterns of young and elderly individuals. As in the previous studies, brain areas were found in both groups where there was differential activation as a function of CR. Most notable were locations where the relation between activation and CR differed across the two groups. These findings provide a basis for a preliminary neural implementation of cognitive reserve. They also suggest t...
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发表时间: 1994-04
期刊: JAMA
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