The developmental origins of voice processing in the human brain.

The developmental origins of voice processing in the human brain.
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DOI:
10.1016/j.neuron.2010.03.001
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发表时间:
2010-03-25
期刊:
影响因子:
16.2
通讯作者:
Friederici, Angela D.
Friederici, Angela D.
中科院分区:
医学1区
文献类型:
--
作者:
Grossmann, Tobias;Oberecker, Regine;Koch, Stefan Paul;Friederici, Angela D.

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对于成年人来说,声音是在上级颞叶皮质的专门大脑区域进行处理的。我们研究的发展,这皮质组织在婴儿期使用近红外光谱。在实验1中,7个月大的婴儿,而不是4个月大的婴儿,在左侧和右侧的上级颞叶皮层对人类声音的反应比非声音声音的反应更大,这表明声音敏感的大脑系统在4到7个月大的时候出现。在实验2中,7个月大的婴儿听了中性,快乐或愤怒韵律的单词。听到情绪韵律导致右半球声音敏感区域的反应增加。此外,在成年人大脑中,右下额叶皮层中的一个负责评价功能的区域对快乐的韵律表现出特别的敏感性。研究结果表明,颞区在发育早期就专门处理声音,而且在婴儿期,情绪就对右半球的声音处理进行了不同的调节。婴儿时期颞叶皮层专门处理人类的声音情绪特别增强婴儿右半球的声音处理婴儿右下额叶皮层对快乐语言的更深评价
In human adults, voices are processed in specialized brain regions in superior temporal cortices. We examined the development of this cortical organization during infancy by using near-infrared spectroscopy. In experiment 1, 7-month-olds but not 4-month-olds showed increased responses in left and right superior temporal cortex to the human voice when compared to nonvocal sounds, suggesting that voice-sensitive brain systems emerge between 4 and 7 months of age. In experiment 2, 7-month-old infants listened to words spoken with neutral, happy, or angry prosody. Hearing emotional prosody resulted in increased responses in a voice-sensitive region in the right hemisphere. Moreover, a region in right inferior frontal cortex taken to serve evaluative functions in the adult brain showed particular sensitivity to happy prosody. The pattern of findings suggests that temporal regions specialize in processing voices very early in development and that, already in infancy, emotions differentially modulate voice processing in the right hemisphere. ► Temporal cortex specializes in processing human voices during infancy ► Emotion specifically enhances voice processing in the right hemisphere in infants ► Deeper evaluation of happy speech in infants' right inferior frontal cortex
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