Asymmetric spermatocyte division as a mechanism for controlling sex ratios.
Asymmetric spermatocyte division as a mechanism for controlling sex ratios.
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DOI:
10.1038/ncomms1160
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发表时间:
2011-01-18
影响因子:
16.6
通讯作者:
Pires-Dasilva A
中科院分区:
文献类型:
--
作者:
Shakes DC;Neva BJ;Huynh H;Chaudhuri J;Pires-Dasilva A
Although Mendel's first law predicts that crosses between XY (or XO) males and XX females should yield equal numbers of males and females, individuals in a wide variety of metazoans transmit their sex chromosomes unequally and produce broods with highly skewed sex ratios. Here we report two modifications to the cellular program of spermatogenesis which, in combination, help explain why males of the free-living nematode species Rhabditis sp. SB347 sire less than 5% male progeny. First, the spermatogenesis program involves a modified meiosis in which chromatids of the unpaired X chromosome separate prematurely, in meiosis I. Second, during anaphase II, cellular components essential for sperm motility are partitioned almost exclusively to the X-bearing sperm. Our studies reveal a novel cellular mechanism for the differential transmission of X-bearing sperm and suggest R. sp. SB347 as a useful model for studying sex chromosome drive and the evolution of new mating systems.
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影响因子:
2.6
作者:
Albertson, Donna G.;Thomson, J. Nichol
通讯作者:
Thomson, J. Nichol
影响因子:
7.8
作者:
ROBERTS, TM;PAVALKO, FM;WARD, S
通讯作者:
WARD, S
影响因子:
2.4
作者:
Félix, MA
通讯作者:
Félix, MA
DOI:
10.1073/pnas.94.1.185
发表时间:
1997-01-07
影响因子:
11.1
作者:
LaMunyon, CW;Ward, S
通讯作者:
Ward, S
DOI:
10.1083/jcb.92.1.121
发表时间:
1982-01
期刊:
The Journal of cell biology
影响因子:
--
作者:
Nelson GA;Roberts TM;Ward S
通讯作者:
Ward S